AKT is a signal transduction protein that plays a central role in inhibiting apoptosis in a variety of tumor types. Constitutive activation of AKT (phosphorylated) has been observed in several human cancers, including lung, breast and prostate. pAKT is associated with poor prognosis as well as chemotherapy and radiotherapy resistance.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Global: 48 hours, Tech-Only (stain only): 24 hours