Probes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter) | RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Acute myeloid leukemia
Note: STAT processing is available by request for PML-RARA. Note STAT along with MD contact name and phone number to receive STAT results.
Bone Marrow Aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable.
Peripheral Blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI.
Fluids: Equal parts RPMI to specimen volume.
Paraffin Block or Cut Slides: Not available.
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
3-5 days. STAT results for PML-RARA, when requested, are reported 12-24 hours from receipt in the NeoGenomics laboratory