Probes: ALK (2p23)
Disease(s): Non-small cell lung carcinoma (NSCLC)
ALK gene rearrangements are found in 3-5% of non-small cell lung carcinoma (NSCLC) and determine likelihood of response to crizotinib (Xalkori®) therapy.
- Paraffin Block: H&E slide (required) plus paraffin block. Circle H&E for tech-only.
- Cut Slides: H&E slide (required) plus 2 unstained slides cut at 4 microns. Circle H&E for tech-only.
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.