Alternative Name
Anaplastic lymphoma kinase
Methodology
FISH
Test Description
Probes: ALK (2p23)
Disease(s): Non-small cell lung carcinoma (NSCLC)
Clinical Significance
ALK gene rearrangements are found in 3-5% of non-small cell lung carcinoma (NSCLC) and determine likelihood of response to crizotinib (Xalkori®) therapy.
Specimen Requirements
  • Paraffin Block: Send paraffin block. Also send circled H&E slide for tech-only (required).
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88377x1 manual.
Turnaround Time
3-5 days
Level of Service
Global
Technical

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.