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AML Non-Favorable Risk Panel
- FISH
Probes: RPN1, MECOM (3q21, 3q26.2) | 5q-, -5 (5p15, 5q31, 5q33 | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | DEK/NUP214 (CAN) t(6;9) | MLL (11q23) | ETV6 (12p13) | 17p- (TP53 17p13.1, NF1 17q11.2) | Probes may be ordered separately.
Disease(s):Acute myeloid leukemia
Turnaround time
3-5 Days
Level of Service
- Global
- Technical Only
New York Approved: Yes
Specimen Requirements
Bone marrow aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable. Peripheral blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable. Fresh, unfixed tissue: Tissue in RPMI. Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 8 slides labeled with specimen type. Fluids: Equal parts RPMI to specimen volume. Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid. Paraffin block or cut slides: Not available. Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
88374x8 automated. Codes may differ if manual analysis is performed.
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025