Alternative Name
Amyloid A, Amyloid P, Amyloid A&P Panel
Methodology
Immunohistochemistry (IHC)
Test Description
Amyloid A and P react with amyloid deposits in many tissues. When accompanied by Congo Red, Amyloid A and P can be used to distinguish primary and secondary amyloidosis. Because these stains are interpreted in context of each other and Congo Red, testing options available to global and tech-only clients differ.
Specimen Requirements
- Global orders: Please order Amyloid A&P Panel and submit a Congo Red-stained slide for our reference (required). If Congo Red staining was not done or the slide is not available, please order a Consult instead so we can coordinate Congo Red staining followed by amyloid A and P staining as indicated. Individual orders for Amyloid A or Amyloid P are not available with global service.
- Tech-only (stain only) orders: Please order Amyloid A and/or Amyloid P as individual stains. The Panel combination is not available with tech-only service, nor is it necessary to submit a Congo Red-stained slide.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
or - One (1) unbaked, unstained slide for H&E staining (required) and two to four (2-4) positively charged unstained slides (all cut at 4-5 microns)
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage & Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
CPT Code(s)*
Panel for global clients: (88342x1, 88341x1) or 88341x2. Single stain for tech-only clients: 88342x1 or 88341x1 for each stain
Turnaround Time
Global: 48 hours, Tech-Only (stain only): 24 hours
Level of Service
Global
Stain Only
New York Approved
Yes