Albumin RNA ISH is a sensitive and specific tool for distinguishing primary hepatocellular carcinoma and intrahepatic cholangiocarcinoma from metastatic adenocarcinoma to the liver or carcinoma of unknown origin in formalin fixed paraffin-embedded tissues. Positive results in this assay provide evidence of liver origin.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and three (3) positively charged unstained slides, all cut at 4-5 microns
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.