Methodology
In Situ Hybridization (ISH)
Test Description
Albumin RNA ISH is a sensitive and specific tool for distinguishing primary hepatocellular carcinoma and intrahepatic cholangiocarcinoma from metastatic adenocarcinoma to the liver or carcinoma of unknown origin in formalin fixed paraffin-embedded tissues. Positive results in this assay provide evidence of liver origin.
Specimen Requirements
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
or - One (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and three (3) positively charged unstained slides, all cut at 4-5 microns
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition
Storage & Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88365x1
Turnaround Time
48 hours
Level of Service
Stain Only
New York Approved
Yes