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Alternative Name
Acute myeloid leukemia
Methodology
FISH
Test Description
Probes: RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Disease(s): Acute myeloid leukemia
Probes may be ordered separately.
Clinical Significance
The AML Favorable-Risk FISH Panel detects translocations associated with favorable prognosis.
Specimen Requirements
  • Bone marrow aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable.
  • Peripheral blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
  • Fresh, unfixed tissue: Tissue in RPMI.
  • Fluids: Equal parts RPMI to specimen volume.
  • Paraffin block or cut slides: Not available.
Storage and Transportation
Refrigerate specimen. Do not freeze. Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88374x3 automated. Codes may differ if manual analysis is performed.
Turnaround Time
3-5 days
Level of Service
Global
Technical

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.