Alternative Name
Acute myeloid leukemia
Methodology
FISH
Test Description
Probes: RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Disease(s): Acute myeloid leukemia
Probes may be ordered separately.
Clinical Significance
The AML Favorable-Risk FISH Panel detects translocations associated with favorable prognosis.
Specimen Requirements
- Bone marrow aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable.
- Peripheral blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
- Fresh, unfixed tissue: Tissue in RPMI.
- Fluids: Equal parts RPMI to specimen volume.
- Paraffin block or cut slides: Not available.
- Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Storage & Transportation
Refrigerate specimen. Do not freeze. Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88374x3 automated. Codes may differ if manual analysis is performed.
Turnaround Time
3-5 days
Level of Service
Global
Technical
New York Approved
Yes