Alternative Name
Cytomegalovirus by ISH
Methodology
In Situ Hybridization (ISH)
Test Description
In situ hybridization for detection of cytomegalovirus (CMV) RNA
Clinical Significance
CMV is a herpesvirus capable of causing serious disease in immunocompromised/ transplant patients and neonates. CMV ISH is useful for detection of primary, latent, and reactivated CMV infections in FFPE tissues.
Specimen Requirements
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
or - One (1) unbaked, unstained slide for H&E staining (required) and three (3) positively charged unstained slides (all cut at 4-5 microns).
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage & Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88365 x 1
Turnaround Time
Global: 3 days, Tech-Only (stain only): 48 hours
Level of Service
Global
Stain Only
New York Approved
Yes