Test by Disease - Myelodysplastic syndrome (MDS) / Chronic myelomonocytic leukemia (CMML)

56 Tests in Listing


AML Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGen...

Flow

ASXL1 Mutation Analysis

Bi-directional sequencing of the majority of exons 13 and 14 of ASXL1, corresponding to amino acids 406-1396.

Molecular

CBL Mutation Analysis

Bi-directional sequencing of exons 8 and 9 of the CBL gene.

Molecular

CD34

CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells and endothelial...

IHC

CD4

CD4, a single chain transmembrane glycoprotein, is found on a T-cell subset (helper/inducer). It is also present on a variety of monocyte-derived cell...

IHC

CD42b

CD42b stains normal platelets, megakaryocytes, and megakaryoblasts. In diseased cells, blasts in transient myeloproliferative disorder are positively ...

IHC

CD68

CD68 is an antibody directed against lysosomes. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variet...

IHC

CD71

CD71 is useful in identifying erythroid precursors with no interference from mature erythrocytes and also in the determination of erythroid leukemia, ...

IHC

Chromosome Analysis

A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic mye...

Cytogenetics

DNMT3A Mutation Analysis

Bi-directional sequencing of exon 26, a mutation hotspot region containing R882 and other mutations. In hematological disease, testing may be performe...

Molecular

ETV6 Mutation Analysis

Bi-directional sequencing of exons 2-7 of the ETV6 gene (formerly called TEL). This assay detects sequence variants rather than ETV6 translocations.

Molecular

Extended Leukemia/Lymphoma Panel - 31 markers

Available as global and tech-only. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11b, CD11c, CD13, CD14, CD15, CD16, CD19, CD20, CD23, CD33, CD...

Flow

FLT3 Mutation Analysis

Detection of internal tandem duplication and exon 20 tyrosine kinase domain (TKD) mutations using bi-directional sequencing. Positive results ident...

Molecular

Glycophorin A

Glycophorin A (sialoglycoprotein alpha) is one of two transmembrane proteins exposed on the outer surface of normal human erythrocytes. This monoclona...

IHC

Hemoglobin A

Hemoglobin A antibody reacts with the alpha chain of adult hemoglobin A. This antibody is useful in the detection of red blood cell precursors. Immuno...

IHC

High Sensitivity PNH Evaluation

Markers are CD14, CD15, CD24, CD45, CD59, CD64, CD235a (Glycophorin A), and FLAER. In validation studies, this assay was shown to detect RBC a...

Flow

Ki67

Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases of the cell ...

IHC

Ki67/Caspase 3 (Double Stain)

The Ki67/caspase-3 antibody cocktail was designed to provide information on apoptosis versus cell proliferation rates. The Ki67 is associated with cel...

IHC

Lysozyme

Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. This antibody labels myeloid cells, his...

IHC

MDS Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGen...

Flow

MDS Extended FISH Panel

Probes: RPN1, MECOM (3q21, 3q26.2) | 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | ...

FISH

MDS FISH Panel (New York)

Probes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (7q31, Cen 7) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter)
Probes may be...

FISH

MDS Standard FISH Panel

Probes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter)
Probe...

FISH

Monocyte Maturation Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGen...

Flow

MPO

Myeloperoxidase (MPO) is an important enzyme used by granulocytes during phagocytic lysis of engulfed foreign particles. In normal tissues and in a va...

IHC

MPO Cytochemical

Special stain (cytochemical). Myeloperoxidase (MPO) is present in granules of myeloid and monocytic cells, but absent from lymphocytes. Therefore MPO ...

IHC

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Molecular

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Cytogenetics

NeoLAB™ FLT3 Mutation Analysis - Liquid Biopsy

Detection of internal tandem duplication and exon 20 tyrosine kinase domain (TKD) mutations using bidirectional sequencing. Positive results identify ...

Molecular

NeoLAB™ KRAS Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of exons 2 and 3 of the KRAS gene. High-sensitivity sequencing is used for enhanced detection of mutations in codons 12, 13,...

Molecular

NeoLAB™ MDS/CMML Profile - Liquid Biopsy

This test is performed by the sequencing of select exons of the genes listed using cell-free plasma DNA/RNA. ASXL1, BCOR, BCORL1, BRAF, CBL, CEBPA,...

Molecular

NeoLAB™ Myeloid Disorders Profile - Liquid Biopsy

This test is performed on cell-free DNA/RNA in peripheral blood plasma by sequencing select exons of the genes listed. ABL1, ASXL1, ATRX, BCOR, BCO...

Molecular

NeoLAB™ NPM1 Mutation Analysis - Liquid Biopsy

PCR and fragment analysis of exon 12 of the NPM1 gene to detect small insertion mutations specific to AML. Positive results are reported quantitativel...

Molecular

NeoLAB™ NRAS Mutation Analysis - Liquid Biopsy

Bi-directional sequencing of NRAS exons 2 and 3 which includes sites of common activating mutations in codons 12, 13, 59, and 61. Testing is performed...

Molecular

NeoTYPE Cancer Exome Profile

The NeoTYPE™ Cancer Exome Profile is performed by massive parallel sequencing of the coding regions in 4813 different cancer related genes. T...

Molecular

NeoTYPE JMML Profile

This test is performed by the sequencing of select exons of the genes listed. BRAF, CBL, CEBPA, FLT3, HRAS, JAK2 V617F, JAK2 Exon 12+14, JAK3, KIT,...

Molecular

NeoTYPE MDS/CMML Profile

This test is performed by the sequencing of select exons of the genes listed unless another method is noted. ASXL1, BCOR, BCORL1, BRAF, CBL, CEBPA,...

Molecular

NeoTYPE Myeloid Disorders Profile

This test is performed by the sequencing of select exons of the genes listed. ABL1, ASXL1, ATRX, BCOR, BCORL1, BRAF, CALR, CBL, CBLB, CBLC, CDKN2A,...

Molecular

NPM1 Mutation Analysis

PCR and fragment analysis of exon 12 of the NPM1 gene to detect small insertion mutations specific to AML. Positive results are reported quantitativel...

Molecular

NRAS Exon 4 Mutation Analysis

Bi-directional sequencing of NRAS exon 4 is performed using PCR primers designed to target hotspot mutations in codons 117 and 146, among other reg...

Molecular

NRAS Mutation Analysis

Bi-directional sequencing of NRAS exons 2 and 3 which includes sites of common activating mutations in codons 12, 13, 59, and 61.

Molecular

PTPN11 Mutation Analysis

Bi-directional sequencing of exons 2-4 of PTPN11.

Molecular

RUNX1 Mutation Analysis

Bi-directional sequencing of exons 4-10 of the RUNX1 gene

Molecular

SETBP1 Mutation Analysis

Bi-directional sequencing of the SETBP1 exon 4 mutation hotspot (covering amino acids 823-941). The locked nucleic acid (LNA) technique is used to inc...

Molecular

SF3B1 Mutation Analysis

RT-PCR and bi-directional sequencing of exons 14-17 of the SF3B1 gene. More than 90% of reported mutations are detected in these exons. This test dete...

Molecular

SRSF2 Mutation Analysis

Bi-directional sequencing of the mutation hotspot region in exon 1 of the SRSF2 gene corresponding to amino acids 57-120.

Molecular

Standard Leukemia/Lymphoma Panel - 24 markers

Available as global and tech-only. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD13, CD14, CD16, CD19, CD20, CD23, CD33, CD34, CD38, CD4...

Flow

TET2 Mutation Analysis

Bi-directional sequencing of the entire coding sequence of the TET2 transcript variant A (2002 amino acids in length).

Molecular

Thrombomodulin (TM)

Thrombomodulin (TM) is a plasma membrane-related glycoprotein that has anticoagulant activity. TM antigen is found in several cell types, including m...

IHC

TP53 Mutation Analysis

Bi-directional sequencing of TP53 exons 4-9.

Molecular

Trichrome

Special stain. Trichrome stains are frequently used to differentiate between collagen and smooth muscle in tumors and to identify increases in collage...

IHC

U2AF1 Mutation Analysis

Bi-directional sequencing of exons 2 and 7 of the U2AF1 gene (also called U2AF35).

Molecular

Universal Fusion/Expression Profile

The Universal Fusion/Expression Profile is a targeted RNA sequencing panel that utilizes next-generation sequencing (NGS) to detect all relevant fusion transcripts in 1,385 genes associated with hematologic or solid tumor cancers. It is especially useful for testing patients with rare diseases. Learn more about the Universal Fusion/Expression Profile...

Molecular

Wright Giemsa

Special stain. The Wright Giemsa stain is used to stain peripheral blood and bone marrow smears for study of blood cell morphology.

IHC

ZRSR2 Mutation Analysis

Bi-directional sequencing of exons 5 and 7-11 of the ZRSR2 gene.

Molecular

 

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