A combination of Melan A/Ki67 is useful in the identification of proliferative index in melanocytic neoplasms. Melan A is a differentiation antigen that is expressed in melanomas, Ki67 is expressed in proliferating cells during late G1, S, M and G2 phases of the cell cycle.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.