In this chapter, Dr. Lyle and Dr. Husain discuss improving detection of EGFR insertion mutation using NGS. Dr. Husain says that PCR can miss more than 50% of EGFR Exon 20 Insertion mutations.
Dr. Lyle and Dr. Husain both understand clinical guidelines to recommend utilizing next-gen sequencing (NGS) for broad molecular profiling to test for biomarkers in lung cancers.