Thyroid Transcription Factory (TTF1) is found is found predominantly in lung and thyroid neoplasms. The utility of TTF1 becomes apparent in the differential diagnosis of primary versus metastatic carcinomas, especially in the lung. This clone is sensitive and may show weak staining in non-lung tissues.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.