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TP63 Rearrangement
- FISH
Probes: TP63 (3q28) | TBL1XR1/TP63 [inv(3)(q26q28)]
Disease(s): Anaplastic large cell lymphoma (ALCL), peripheral T-cell lymphoma (PTCL)
Note: Probes are not orderable separately; concurrent analysis is necessary due to proximity of breakpoints in the most common fusion rearrangement.
Turnaround time
3-5 Days
Level of Service
- Global
- Technical Only
New York Approved: Yes
Specimen Requirements
Bone Marrow Aspirate: N/A Peripheral Blood: N/A Fresh, Unfixed Tissue: N/A Fluids: N/A Paraffin Block: H&E slide (required) plus paraffin block. Circle H&E for tech-only. Cut Slides: H&E slide (required) plus 2 unstained slides cut at 4 microns. Circle H&E for tech-only.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
88377x2 manual or 88374x2 automated
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025