Get in touch
Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.
Plasma Cell Myeloma Prognostic FISH Panel
- FISH
Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | 13q- (13q14, 13q34) | IgH/MAF t(14;16) | IgH/MAFB t(14;20) |17p- (TP53 17p13.1, NF1 17q11.2) Probes may be ordered separately. Disease(s): Plasma cell myeloma, multiple myeloma. Note: Plasma cell enrichment will be performed on bone marrow samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection.
Turnaround time
3-5 Days
Level of Service
- Global
- Technical Only
New York Approved: Yes
Specimen Requirements
Bone Marrow Aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable. Peripheral Blood: Plasma cell enrichment was not validated using peripheral blood; therefore, it is not recommended as a screening specimen unless increased plasma cells are seen on blood smear. 2-5mL sodium heparin tube. EDTA tube is acceptable. Fresh, Unfixed Tissue: Tissue in RPMI Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 7 slides labeled with specimen type. Fluids: Equal parts RPMI to specimen volume. Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid. Paraffin Block or Cut Slide: N/A Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Storage and Transportation
Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
88374x7 automated or 88377x7 manual
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025