Methodology
Immunohistochemistry (IHC)
Test Description
CD103 antibody reacts with the integrin subunit CD103 cell surface antigen, which is expressed in intraepithelial T-lymphocytes, hairy cell leukemia, enteropathy associated T-cell lymphoma, and some splenic marginal zone lymphomas.
Staining description: Membranous
Specimen Requirements
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
or - One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage & Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88342 x 1 or 88341 x 1
Turnaround Time
24 Hours
Level of Service
Stain Only
New York Approved
Yes
References
- Morgan, EA, et al. Immunohistochemical Detection of Hairy Cell Leukemia in Paraffin Sections Using a Highly Effective CD103 Rabbit Monoclonal Antibody. Am J Clin Pathol. 2013 Feb;139(2):220-230