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Methodology
Immunohistochemistry (IHC)
Test Description

CD103 antibody reacts with the integrin subunit CD103 cell surface antigen, which is expressed in intraepithelial T-lymphocytes, hairy cell leukemia, enteropathy associated T-cell lymphoma, and some splenic marginal zone lymphomas.

Staining description: Membranous

Specimen Requirements
  • A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
    or
  • One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
  • Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

CPT Code(s)*
88342 x 1 or 88341 x 1
Turnaround Time
24 Hours
References
Morgan, EA, et al. Immunohistochemical Detection of Hairy Cell Leukemia in Paraffin Sections Using a Highly Effective CD103 Rabbit Monoclonal Antibody. Am J Clin Pathol. 2013 Feb;139(2):220-230
New York Approved
Yes
Level of Service
Stain Only

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.