Displaying 126 - 150 of 577
CD68 is an antibody directed against lysosomes. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, lamina…
Immunohistochemistry (IHC)
CD68 protein belongs to a family of lysosomal glycoprotein. CD68 Clone PG-M1 labels macrophages and shows a greater specificity for monocytes and macrophages in hematolymphoid tumors. It is useful in the classification of acute myeloid leukemia (AML…
Immunohistochemistry (IHC)
CD7 is expressed on the majority of immature and mature T-lymphocytes and T-cell leukemia. It is also found on natural killer cells, and a small subpopulation of normal and malignant B-cells. CD7 antibody can be useful for detection of T-cell…
Immunohistochemistry (IHC)
CD71 is useful in identifying erythroid precursors with no interference from mature erythrocytes and also in the determination of erythroid leukemia, benign erythroid proliferative disorders, and myelodysplastic syndrome.
Immunohistochemistry (IHC)
CD79a first appears at the pre B-cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B-cell type, B-cell lines, B-cell lymphomas, and in…
Immunohistochemistry (IHC)
CD8 is a T-cell marker for the detection of cytotoxic/suppressor T-cells. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells, and bone marrow cells. This antibody is useful in evaluating T-cell lymphomas.
Immunohistochemistry (IHC)
CD99 (MIC2 gene product, E2) antigen is strongly expressed by Ewing sarcoma cells, primitive peripheral neuroectodermal tumors, and lymphoblastic leukemia/lymphoma.
Immunohistochemistry (IHC)
Among cyclin/CDK proteins, CDK4 and cyclin D1 are the most frequently activated by somatic genetic alterations in multiple tumor types. CDK4 antibody assists in distinguishing atypical lipomatous tumor well-differentiated liposarcoma (WDL) (positive…
Immunohistochemistry (IHC)
Probes: CDKN2A (p16) (9p21) | Centromere 9Disease(s): Acute Lymphoblastic Leukemia (ALL)
FISH
Probes: CDKN2A (p16) (9p21) | Centromere 9Disease(s):  Mesothelioma
FISH
CDX2 is an intestine specific transcription factor that regulates both the proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The…
Immunohistochemistry (IHC)
CDX2 is a transcription factor expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the…
Immunohistochemistry (IHC)
Carcinoembryonic antigen (CEA) is usually demonstrated as a linear labeling of the apical poles of cells lining the glandular lumen and occasionally as weak staining near the apex of normal colonic epithelial cells. Tumors tend to display an…
Immunohistochemistry (IHC)
Polyclonal carcinoembryonic antigen (CEA) antibody stains a larger percentage of cholangiocarcinomas compared to hepatocellular carcinomas. Approximately 95% of olangiocarcinomas are stained diffusely and strongly with polyclonal CEA, whereas show a…
Immunohistochemistry (IHC)
Bi-directional sequencing of the relevant coding region and fragment analysis for detection of sequence variant and internal tandem duplication mutations. The SNP genotype at rs34529039 is reported. Testing is performed on plasma for increased…
Molecular
Probes: CEN 1 (1p11.1-q11.1)Disease(s): Molar pregnancy vs. partial mole This test is currently available on a global basis only.
FISH
Cytochemical stain.
Immunohistochemistry (IHC)
Chromogranin is present in several elements of the diffuse neuroendocrine system (DNES), including anterior pituitary, thyroid perifollicular C cells, parathyroid chief cells, pancreatic islet cells, intestinal enterochromaffin cells and tumors…
Immunohistochemistry (IHC)
A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic myeloid and lymphoid disorders are examined cytogenetically in order to establish the exact nature of the…
Cytogenetics
Cytokeratins 10 and 13 are intermediate-size, acidic type I cytokeratins (molecular mass of 56.5 kDa). CK10/13 cocktail is expressed in all suprabasal cells of normal stratified squamous epithelium, although it is absent in the basal layer. CK10/13…
Immunohistochemistry (IHC)
CK903 (34betaE12) is a high molecular weight cytokeratin present in all squamous epithelium and their carcinomas. This antibody recognizes cytokeratins 1, 5, 10 and 14 that are found in complex epithelia. There has been no reactivity with cells…
Immunohistochemistry (IHC)
This cytokeratin cocktail can be useful in differentiation of the squamous cell carcinomas and adenocarcinomas. The 34bE12 clone recognizes cytokeratin (CK) 1, 5, 10 and 14. It is reactive with stratified epithelia, myoepithelial and basal cells of…
Immunohistochemistry (IHC)
Anti-cytokeratin clone OSCAR (CK OSCAR) demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, OSCAR is reactive with most epithelial types, including bile ducts and hepatocytes in liver, bladder epithelium, breast ducts,…
Immunohistochemistry (IHC)
Cytokeratin 14 (CK14) belongs to the type A (acidic) subfamily of high molecular weight keratins and exists in combination with keratin 5. CK14 has been studied as a prognostic marker in breast cancer. CK14 distinguishes stratified epithelial cells…
Immunohistochemistry (IHC)
Cytokeratin 17 (CK17) is an effective marker to distinguish myoepithelial cells from luminal epithelium of various glands (mammary, sweat, salivary, bronchial, tracheal, laryngeal, esophageal) and benign from malignant forms of tumors, e.g. mammary…
Immunohistochemistry (IHC)