Molecular
… or in combination with BRAF, HRAS and NRAS in the RAS/RAF Panel . KRAS testing in non-small cell lung cancer may … or in combination with BRAF, HRAS and NRAS in the RAS/RAF Panel . KRAS testing in non-small cell lung cancer may …
FISH
… Disease(s): Eosinophilia Also available as part of ALL FISH Panel (Ph-Like) Clinical Significance JAK2 (9p24.1) … Disease(s): Eosinophilia Also available as part of ALL FISH Panel (Ph-Like) … 88374x1 automated or 88377x1 if manual …
Molecular
… test may be ordered separately or as part of the MPN Reflex Panel. Testing is approved for specimens from the state of … test may be ordered separately or as part of the MPN Reflex Panel. Testing is approved for specimens from the state of …
Immunohistochemistry (IHC)
… in melanosomes. Melan A is a useful addition to melanoma panels since it is specific for melanocytic lesions. Both … in melanosomes. Melan A is a useful addition to melanoma panels since it is specific for melanocytic lesions. Both …
Immunohistochemistry (IHC)
… adenocarcinoma as squamous cell carcinoma. These findings strongly support the routine use of p40 for the … adenocarcinoma as squamous cell carcinoma. These findings strongly support the routine use of p40 for the …
Immunohistochemistry (IHC)
… P Alternative Name Amyloid A, Amyloid P, Amyloid A&P Panel Methodology Immunohistochemistry (IHC) Test … Requirements Global orders: Please order Amyloid A&P Panel and submit a Congo Red-stained slide for our reference … order Amyloid A and/or Amyloid P as individual stains. The Panel combination is not available with tech-only service, …
Molecular
… subtypes through next-generation sequencing (NGS): ABL1, ABL2, ALK, ARHGEF1, ARID1A, ARID2, ASXL1, ATM, … subtypes through next-generation sequencing (NGS): ABL1, ABL2, ALK, ARHGEF1, ARID1A, ARID2, ASXL1, ATM, …
Flow Cytometry
… Please provide Date and Time of Collection and recent transfusion history. Storage & Transportation Specimens should be … Please provide Date and Time of Collection and recent transfusion history. … Specimens should be received at …
Molecular
… via our online test order system or by using the current NGS Solid Tumor Pathology Requisition. Storage & … via our online test order system or by using the current NGS Solid Tumor Pathology Requisition. … Use cold pack for …
Molecular
… and G1202R. Note: This test is not designed to detect ALK fusions. To test for ALK rearrangement/fusions, either ALK for NSCLC FISH or Lung NGS Fusion Panel (Complete) are suggested. Specimen Requirements FFPE …
FISH
… protuberans (DFSP) commonly has the COL1A1-PDGFB fusion gene and other variants of PDGFB fusion that are related to DFSP pathogenesis and targeted … protuberans (DFSP) commonly has the COL1A1-PDGFB fusion gene and other variants of PDGFB fusion that are …
FISH
… and various solid tumors Clinical Significance FGFR2 fusions are under active clinical study in a range of solid … available to certain cholangiocarcinoma patients. FGFR2 fusions occur at highest frequency in intrahepatic … a break-apart FISH probe to detect the presence of FGFR2 fusions (translocations). Fusion partners of FGFR2 are not …
FISH
… Leukemia Probes: NUP98 (11p15.4) Clinical Significance Fusions of the nucleoporin 98 (NUP98) gene with more than 30 … malignancies including AML, MDS, and T-ALL. Recurring NUP98 fusions, such as NUP98-NSD1, NUP98-JARID1A, and NUP98-HOXA9, … 11 … 19 … Use of this break-apart FISH test to detect NUP98 fusions (rearrangements) may be useful to further classify …
FISH
… (SBC), and congenital mesoblastic nephroma (CMN). FISH panel testing for NTRK1, 2, and 3 rearrangements (coming … soon) is recommended for pediatric glioma, papillary thyroid carcinoma (PTC) and other tumors. The NTRK3 gene …
FISH
… bone cysts Clinical Significance USP6 gene rearrangements (fusions) are commonly found in nodular fasciitis (NF), … 88377x1 manual … 24 … 26 … 28 … USP6 gene rearrangements (fusions) are found in nodular fasciitis, aneurysmal bone …
Molecular
… or in combination with BRAF, HRAS and KRAS in the RAS/RAF Panel . Specimen Requirements Peripheral blood: 5 mL in EDTA … … NRAS, NRAS Exon 2, NRAS Exon 3, RAS mutations, RAS/RAF Panel, NY, New York, codon 117, codon 146, exon 4 … 61 … …
FISH
… probe is available separately or as part of the NHL FISH Panel . Specimen Requirements Bone Marrow Aspirate: 1-2mL … large cell lymphoma, NHL … ALK translocation, ALK fusion … 40 … Bone Marrow Aspirate: 1-2mL Sodium Heparin …
FISH
… (M/RCLS). The DDIT3 locus was formerly named CHOP. Fusion of DDIT3 and FUS genes in t(12;16)(q13;p11) is … by this FISH test. For that purpose, please see the NGS Sarcoma Fusion Profile . Specimen Requirements Bone marrow aspirate: …
FISH
… synovial sarcoma is t(X;18)(p11.2;q11.2) which results in fusion of SS18 with one of the SSX genes on the X … by this FISH test. For that purpose, please see the NGS Comprehensive Sarcoma Fusion Profile . Specimen Requirements Bone marrow …
FISH
… are the hallmark and pathognomic molecular findings of Ewing sarcoma (almost all ES) and "Ewing-like … by this FISH test. For that purpose, please see the NGS Sarcoma Fusion Profile which may be ordered separately or as a …
Molecular
… 50% of cutaneous squamous cell carcinoma and up to 30% of thyroid cancers. In thyroid cancers, TERT promoter mutations are detected in … and 70% of anaplastic carcinomas. In papillary thyroid carcinomas, the co-presence of mutations in the TERT …
Molecular
… pancreas, prostate, melanoma, head & neck, bladder, thyroid, kidney, ovarian, liver, thyroid, breast, and lung*. Tissue testing is recommended …
FISH
… Available separately or as part of the AML FISH Panel. Specimen Requirements Bone Marrow Aspirate: 1-2mL … (11q23) is available separately or as part of the AML FISH Panel. … MLL, mixed-lineage leukemia … 40 … Bone Marrow …
FISH
… B-cell non-Hodgkin lymphoma Clinical Significance This FISH panel detects proximal gains and distal losses of chromosome … automated or 88377x1 manual … 10 … 15 … 42 … 21 … This FISH panel detects proximal gains and distal losses of chromosome …
FISH
… in B-lineage acute lymphoblasticleukaemia without recurrent fusion genes across age cohorts. Brit J Haematol . … in B-lineage acute lymphoblasticleukaemia without recurrent fusion genes across age cohorts. Brit J Haematol . …