Methodology
FISH
Test Description

Probes: Centromere X | Centromere Y
Note: Testing is performed only on a global basis at this time.
Disease(s): Molar pregnancy (hydatidiform mole), partial mole, triploidy

Clinical Significance

Along with morphological exam, FISH for chromosomes X and Y can be useful in differentiating true molar pregnancy (46, XX) from partial molar triploid pregnancy (69, XXY or XYY).

Specimen Requirements
  • Fresh, unfixed tissue: N/A
  • Paraffin block: Send paraffin block
Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

CPT Code(s)*
88377x1 manual or 88374x1 automated
Turnaround Time

5-7 days

Level of Service
Global

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.