Available as global test only. Markers are VB1, VB2, VB3, VB4, VB5.1, VB5.2, VB5.3, VB7.1, VB7.2, VB8, VB9, VB11, VB12, VB13.1, VB13.2, VB13.6, VB14, VB16, VB17, VB18, VB20, VB21.3, VB22, and VB23 (24 markers). Two additional T-cell markers are used to identify the population of interest and the markers vary from case to case.
Useful in identification of clonal T-cell populations to aid in diagnosis of T-cell lymphoproliferative disorders. Clonal T-cell populations can be identified in some reactive conditions and in some healthy elderly patients. Correlation with morphology, clinical history, and other diagnostic information is necessary for diagnosis.
- Bone marrow aspirate or peripheral blood: 1-2 mL EDTA preferred. 1-2 mL minimum in sodium heparin tube or ACD (pale yellow/no gel separator) is acceptable. Please provide recent CBC report.
- Bone marrow core: 1-2 cm minimum core length in RPMI.
- Fresh, unfixed tissue: 0.2 cm3 minimum in RPMI.
- Fluids and FNAs: Equal parts RPMI and specimen.
Specimens should be received at NeoGenomics within 72 hours from collection to assure sample integrity and acceptable cell viability. Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.