Available as global test only. Markers are VB1, VB2, VB3, VB4, VB5.1, VB5.2, VB5.3, VB7.1, VB7.2, VB8, VB9, VB11, VB12, VB13.1, VB13.2, VB13.6, VB14, VB16, VB17, VB18, VB20, VB21.3, VB22, and VB23 (24 markers). Two additional T-cell markers are used to identify the population of interest and the markers vary from case to case.
Useful in identification of clonal T-cell populations to aid in diagnosis of T-cell lymphoproliferative disorders. Clonal T-cell populations can be identified in some reactive conditions and in some healthy elderly patients. Correlation with morphology, clinical history, and other diagnostic information is necessary for diagnosis.
- Bone Marrow Aspirate: 1-2 mL EDTA. Sodium heparin is acceptable. Lithium heparin or ACD (pale yellow/no gel separator) is not acceptable. Please provide recent CBC report.
- Peripheral Blood: 1-2 mL EDTA. Sodium heparin is acceptable. Lithium heparin or ACD (pale yellow/no gel separator) is not acceptable. Please provide recent CBC report.
- Fresh Bone Marrow Core Biopsy: 1-2cm core (length) tissue in RPMI
- Fresh/Unfixed Tissue: 0.2 cm3 minimum in RPMI
- Fluids and FNAs: Equal parts RPMI and specimen volume
- NY Clients: Please provide Date and Time of Collection.
- Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Specimens should be received at NeoGenomics within 72 hours from collection to assure sample integrity and acceptable cell viability. Note: New York State samples must be received within 48 hours from collection per NYS requirements. Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.