Test by Disease - T-cell lymphoma

45 Tests in Listing


ALK (2p23) for lymphoma

Probes: ALK (2p23)
Disease(s): Anaplastic large cell lymphoma, NHL

FISH

ALK-1 (for heme cases)

The ALK1 (ALK1 cline) antibody labels normal human ALK protein and the NPM-ALK chimeric protein, and is a useful tool for the identification of the su...

IHC

B-Cell Gene Rearrangement

Detection of clonal IgH gene rearragements by PCR of IgH framework regions 1, 2, 3 and joining regions. In addition, Ig Kappa gene rearrangement analy...

Molecular

CD10

CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is expressed in early lymphoid progenitors and normal germinal center cells. It...

IHC

CD2

CD2, the E-rosette receptor, is an extremely broad T-cell marker. This antibody immunostains the vast majority of T-cells and a subset of natural kill...

IHC

CD21

CD21 (CR2, C3d receptor and EBV receptor) is expressed strongly on mature B-cells, follicular dendritic cells (FDC) and weakly on immature thymocytes ...

IHC

CD25

The interleukin-2 receptor is designated CD25. Originally isolated from T-lymphocytes, it is now known to be expressed on hairy cell leukemia and adu...

IHC

CD3

The CD3 antigen is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T-cell l...

IHC

CD30

CD30 is a lymphocyte activation antigen, related to tumor necrosis factor. It is expressed in activated B-, T- and NK cells. Positive staining is seen...

IHC

CD34

CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells and endothelial...

IHC

CD43

CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is a cell surface glycoprotein that is expressed on all thymocytes, T-cells, and cells...

IHC

CD45RO

CD45RO (an isoform of leukocyte common antigen) reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within ...

IHC

CD5

CD5, a transmembrane protein, is found on most thymocytes and immature peripheral T-cells. It stains normal B-cells of mantle zone of spleen and lymph...

IHC

CD56

CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally-derived cell lines, tissues ...

IHC

CD57

CD57 is expressed on subpopulations of peripheral blood mononuclear cells, NK active cells and T-cells. Hematopoietic malignancies that are CD57+ incl...

IHC

CD7

CD7 is expressed on the majority of immature and mature T-lymphocytes and T-cell leukemia. It is also found on natural killer cells, and a small subpo...

IHC

CD8

CD8 is a T-cell marker for the detection of cytotoxic/suppressor T-cells. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null c...

IHC

Chromosome Analysis

A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic mye...

Cytogenetics

CXCL13

CXCL13 is useful marker in the diagnosis of angioimmunoblastic T-cell lymphoma

IHC

EBER

This probe set labels all latent EBV-infected cells, including EBV-positive lymphoblastoid cell lines and EBV infected B-cell immunoblasts in infectio...

ISH

EBV (LMP1)

This antibody reacts strongly with Epstein Barr Virus (EBV)-positive lymphoblastoid cell lines and EBV infected B-cell immunoblasts in infectious mono...

IHC

EMA

Epithelial Membrane Antigen (EMA) antibody stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squ...

IHC

Granzyme B

Granzyme B antibody labels activated human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. This marker can be a useful tool for the ident...

IHC

IgH (14q32)

Probes: IgH (14q32)
Disease(s): Lymphoma, NHL, multiple myeloma, MGUS

FISH

Ki67

Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases of the cell ...

IHC

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Molecular

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Cytogenetics

NeoTYPE™ AITL/Peripheral T-Cell Lymphoma Profile

The NeoTYPE AITL/Peripheral T-Cell Lymphoma Profile is performed by the sequencing of select exons in the genes IDH1, IDH2, DNMT3A, TET2 and RHOA...

Molecular

NeoTYPE™ Cancer Exome Profile

The NeoTYPE™ Cancer Exome Profile is performed by massive parallel sequencing of the coding regions in 4813 different cancer related genes. Test order...

Molecular

PD1

Programmed death-1 (PD-1) is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PD-1 is a marker of angioimmunoblastic lymphoma and sugg...

IHC

Perforin

Perforin is a protein found in cytoplasmic granules of cytotoxic T-lymphocytes (CTLs). CTLs bind to cells that express foreign antigens and induce the...

IHC

RHOA Mutation Analysis

Bi-directional sequencing of the gene RHOA. The locked nucleic acid (LNA) technique is used to increase detection sensitivity for the G17V mutation...

Molecular

Standard Leukemia/Lymphoma Panel - 24 markers

Available as global and tech-only. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD13, CD14, CD16, CD19, CD20, CD23, CD33, CD34, CD38, CD4...

Flow

T&B Tissue Flow Panel

Stand-alone test. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD19, CD20, CD23, CD34, CD38, CD45, CD56, kappa, and lambda (17 markers).&...

Flow

Tau

Tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of ...

IHC

T-Cell Receptor Beta Gene Rearrangement

This test provides qualitative detection of monoclonal T-cell receptor (TCR) beta gene rearrangements by PCR and fragment analysis according to BIOMED-2 consensus primer design. This test may be ordered concurrently with or after negative results in our T-Cell Receptor Gamma Gene Rearrangement...

Molecular

T-Cell Receptor Gamma Gene Rearrangement

Detection of clonal T-cell receptor gamma (TCRG) gene rearrangements by PCR of variable and joining regions. T-Cell Receptor Beta Gene Rearrangemen...

Molecular

T-Cell Receptor/LGL Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGen...

Flow

T-Cell Therapy Flow Panel

Available as global and tech-only. Available as stand-alone test (as described here) or as add-on to panels. Markers are CD3, CD4, CD7, CD8, CD25, ...

Flow

TCL1

T-cell leukemia/lymphoma protein 1 (TCL1) is normally found in the nucleus and cytoplasm of lymphoid lineage cells during early embryogenesis. Chromos...

IHC

TCL1

Probes: TCL1 (14q32.1)
Disease(s): mature T-cell leukemia, T-cell prolymphocytic leukemia (T-PLL), adult...

FISH

TP53 Mutation Analysis

Bi-directional sequencing of TP53 exons 4-9.

Molecular

Universal Fusion/Expression Profile

The Universal Fusion/Expression Profile is a targeted RNA sequencing panel that utilizes next-generation sequencing (NGS) to detect all relevant fusion transcripts in 1,385 genes associated with hematologic or solid tumor cancers. It is especially useful for testing patients with rare diseases. Learn more about the Universal Fusion/Expression Profile...

Molecular

V-Beta T-Cell Clonality

Available as global test only. Markers are VB1, VB2, VB3, VB4, VB5.1, VB5.2, VB5.3, VB7.1, VB7.2, VB8, VB9, VB11, VB12, VB13.1, VB13.2, VB13.6, VB1...

Flow

Wright Giemsa

Special stain. The Wright Giemsa stain is used to stain peripheral blood and bone marrow smears for study of blood cell morphology.

IHC

 

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