Displaying 1 - 20 of 102 tests
CA125
CA125 reacts with most epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. CA125 is a useful tumor marker for ovarian carcinomas; however, CA125 has also been described in other neoplasms such as seminal vesicle and anaplastic lymphomas. No reactivity has
Immunohistochemistry (IHC)
CA19.9
In normal tissues, the CA19.9 antigen has been demonstrated in ductal epithelium of the breast, kidney, salivary gland, sweat glands, respiratory epithelium of the lung, colon epithelium, pancreatic acini and ducts, biliary epithelium in the liver and prostate epithelium. Gastrointestinal carcinomas
Immunohistochemistry (IHC)
Calcitonin
Calcitonin is secreted by thyroidal parafollicular cells of neuroectodermal origin, probably in response to hypercalcemia. The IHC demonstration of calcitonin is important: (1) For identification of early or microscopic medullary thyroid cancer (MTC), (2) To identify an MTC in the absence of amyloid
Immunohistochemistry (IHC)
Calcium Stain
Special stain.
Immunohistochemistry (IHC)
Caldesmon
Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon have been identified. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle and a subset of myoepithelial cells, whereas l
Immunohistochemistry (IHC)
Calponin
Calponin, a calmodulin, is involved in the regulation of smooth muscle contraction. The expression of calponin is restricted to smooth muscle cells. Two isoforms of calponin exist with molecular weights of 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the
Immunohistochemistry (IHC)
CALR Mutation Analysis
Bi-directional sequencing of exon 9 of the CALR (calreticulin) gene with fragment length analysis for enhanced detection of low levels of insertion/deletion mutations.Testing is approved for specimens from the state of New York. Read more about the CALR Mutation Analysis.
Molecular
Calretinin
Calretinin is the most specific and reproducible positive marker of epithelial mesothelioma. Calretinin is a calcium-binding protein similar to S100 protein. It is found in the central and peripheral nervous system and in a wide spectrum of non-neural cells, including steroid-producing cells of
Immunohistochemistry (IHC)
CAM 5.2
Anti-Cytokeratin (CAM 5.2) has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, Mr 48 and 52 Kd. Cytokeratin 8 is present on secretory epithelia of normal human tissue but not on stratified squamous epithelium. CAM 5.2 stains most epithelial derived
Immunohistochemistry (IHC)
Carbonic Anhydrase IX (CA IX)
Carbonic anhydrase IX (CAIX) is a cell surface transmembrane protein, which is predominantly found in the gastrointestinal tract and gall bladder. The glandular regions of normal colon are reported to be negative, but in the case of adenocarcinoma, the glands are positive. CAIX is also expressed in
Immunohistochemistry (IHC)
CARD11 Mutation Analysis
Bi-directional sequencing of exons 5 and 6 of the CARD11 gene. Testing is available separately or as part of the NeoTYPE™ Lymphoma Profile.
Molecular
Cat Scratch
The causative bacterial agent of cat scratch disease has been identified as Bartonella henselae. This monoclonal antibody identifies bartonella henselae in formalin-fixed, paraffin-embedded (FFPE) tissues and does not cross-react with Spirochete, Helicobacter pylori and Mycobacterium tuberculosis.
Immunohistochemistry (IHC)
Cathepsin D
Cathepsin D is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and connective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a
Immunohistochemistry (IHC)
CBFB inv(16)
Probes: CBFB inv(16), t(16;16) Disease(s): AML, AMML (AML-M4E)
FISH
CBL Mutation Analysis
Bi-directional sequencing of exons 8 and 9 of the CBL gene.
Molecular
CCND1(BCL1)/IgH t(11;14)
Probes: CCND1/IgH t(11;14) Disease(s): Mantle cell lymphoma, NHL
FISH
CD10
CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is expressed in early lymphoid progenitors and normal germinal center cells. It is almost always present on the surface of precursor B-lymphoblastic and Burkitt lymphomas and much less frequently on precursor T-lymphoblastic
Immunohistochemistry (IHC)
CD117 cKIT
CD117 (cKit) is a transmembrane receptor tyrosine kinase. It is expressed in many tissues and cells, such as tissue mast cells, skin basal cells, melanocytes, breast glandular epithelial cells, dermal sweat gland, esophageal glands, testicular and ovarian interstitial cells. Abnormal expression of
Immunohistochemistry (IHC)
CD11c
In normal cells, CD11c is expressed on activated CD4/CD8+ T cells, granulocytes, lymphocytes, macrophages, and NK cells. In diseased, cells, CD11c is detected on acute myeloid leukemia (AML)-M4 and M5, hairy cell leukemia, lymphoplasmacytic lymphoma (81%), small lymphocytic lymphoma (SLL), splenic
Immunohistochemistry (IHC)
CD123
CD123 labels plasmacytoid dendritic cells and is useful in diagnosing neoplasms derived from these cells as well as reactive conditions, such as histiocytic necrotizing lymphadentis.
Immunohistochemistry (IHC)