Displaying 1 - 22 of 22 tests
Perforin Perforin is a protein found in cytoplasmic granules of cytotoxic T-lymphocytes (CTLs). CTLs bind to cells that express foreign antigens and induce them to lyse. Perforin expression is significantly…
Immunohistochemistry (IHC)
Chromosome Analysis A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic myeloid and lymphoid disorders are examined…
Cytogenetics
ALK for Lymphoma Probes: ALK (2p23)Disease(s): Anaplastic large cell lymphoma, NHL
FISH
High-Grade/Large B-Cell Lymphoma Panel (NY and non-NY) Probes: BCL6 (3q27) | MYC (8q24) | IgH/BCL2 t(14;18) | Optional probes: MYC/IgH/CEN8 t(8;14) [available to all clients] and BCL2 (18q21) [non-New York clients only]Disease(s): B-cell lymphoma,…
FISH
IgH (14q32) Probes: IgH (14q32)Disease(s): Lymphoma, NHL, multiple myeloma, MGUS
FISH
Non-Hodgkin's Lymphoma (NHL) FISH Panel Probes: ALK (2p23) | BCL6 (3q27) | MYC (8q24) | CCND1/IgH t(11;14) | IgH (14q32) | IgH/BCL2 t(14;18) | MALT1 (18q21) Probes may be ordered separately.Disease(s): NHL
FISH
TIA1 TIA1 (T-cell intracytoplasmic antigen) monoclonal antibody reacts with a 15 kDa cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. Most anaplastic large…
Immunohistochemistry (IHC)
Wright Giemsa Cytochemical stain. The Wright Giemsa stain is used to stain peripheral blood and bone marrow smears for study of blood cell morphology.
Immunohistochemistry (IHC)
Ki67 Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases of the cell cycle, while cells in the G0 (quiescent) phase are…
Immunohistochemistry (IHC)
MPO Cytochemical Cytochemical stain. Myeloperoxidase (MPO) is present in granules of myeloid and monocytic cells, but absent from lymphocytes. Therefore MPO is an important marker for discriminating myeloid vs.…
Immunohistochemistry (IHC)
T-Cell Therapy Flow Panel Available as global and tech-only. Available as stand-alone test (as described here) or as add-on to panels. Markers are CD3, CD4, CD7, CD8, CD25, CD26, CD30, CD45, CD52, and CD279 (10 markers).
Flow Cytometry
Standard Leukemia/Lymphoma Panel - 24 markers Available as global and tech-only. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD13, CD14, CD16, CD19, CD20, CD23, CD33, CD34, CD38, CD45, CD56, CD64, CD117, HLA-DR, kappa, and lambda.
Flow Cytometry
V-Beta T-Cell Clonality Available as global test only. Markers are VB1, VB2, VB3, VB4, VB5.1, VB5.2, VB5.3, VB7.1, VB7.2, VB8, VB9, VB11, VB12, VB13.1, VB13.2, VB13.6, VB14, VB16, VB17, VB18, VB20, VB21.3, VB22, and VB23 (…
Flow Cytometry
ALK-1 (for heme cases) The ALK1 (ALK1 cline) antibody labels normal human ALK protein and the NPM-ALK chimeric protein, and is a useful tool for the identification of the subgroup of anaplastic large-cell lymphomas (ALCL)…
Immunohistochemistry (IHC)
CD3 The CD3 antigen is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T-cell lineage. It has a cytoplasmic expression at early…
Immunohistochemistry (IHC)
CD30 CD30 is a lymphocyte activation antigen, related to tumor necrosis factor. It is expressed in activated B-, T- and NK cells. Positive staining is seen in infectious mononucleosis, lymphocytes…
Immunohistochemistry (IHC)
EMA Epithelial Membrane Antigen (EMA) antibody stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squamous epithelium. Hepatocellular carcinoma,…
Immunohistochemistry (IHC)
BTK Inhibitor Primary Susceptibility Panel Concurrent analysis of the following by bi-directional sequencing: CARD11 exons 5 and 6, CD79B exon 5 including common Y196 mutations, CXCR4 C-terminus region, and MYD88 exon 5 including the L265P…
Molecular
T&B Tissue Flow Panel Stand-alone test. Markers are CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD19, CD20, CD23, CD34, CD38, CD45, CD56, kappa, and lambda (17 markers). 
Flow Cytometry
DUSP22-IRF4 Rearrangement Probes: DUPS22-IRF4 gene region at 6p25.3Disease(s): Anaplastic Large Cell Lymphoma (ALCL), large B-cell lymphoma  
FISH
High-Grade B-Cell Lymphoma Reflex FISH Panel (Non-New York) Probes: MYC (8q24). If rearranged, reflex to concurrent BCL2 (18q21) and BCL6 (3q27).Disease(s): B-cell lymphoma, double-hit lymphoma, triple-hit lymphoma Note: This test is available on a global…
FISH
TP63 Rearrangement Probes: TP63 (3q28) | TBL1XR1/TP63 [inv(3)(q26q28)] Disease(s): Anaplastic large cell lymphoma (ALCL), peripheral T-cell lymphoma (PTCL) Note: Probes are not orderable separately; concurrent…
FISH