Probes: FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | IgH/MAF t(14;16) | IgH/MAFB t(14;20)
Probes for each translocation may be ordered separately.
This panel is available separately or by reflex after the Plasma Cell Myeloma FISH Panel if it detects IgH rearrangement.
Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize t(4;14) testing unless directed otherwise by our client.
Bone Marrow Aspirate: 1-2mL Sodium Heparin Tube. EDTA tube is acceptable
Peripheral Blood: Not recommended as a screening specimen unless increased plasma cells are seen on blood smear. 2-5mL sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI
Fluids: Equal parts RPMI to specimen volume
Paraffin Block or Cut Slide: N/A
Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Specimens should be received in our laboratory within 72 hours of collection.