Probe(s): PDGFB (22q13.1)
Disease(s): Dermatofibrosarcoma protuberans (DFSP)
Dermatofibrosarcoma protuberans (DFSP) commonly has the COL1A1-PDGFB fusion gene and other variants of PDGFB fusion that are related to DFSP pathogenesis and targeted therapies.
- Paraffin Block: Send paraffin block. Also send circled H&E slide for tech-only (required).
- Cut Slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Circle H&E slide for tech-only.
- Bone Marrow Aspirate: N/A
- Peripheral Blood: N/A
- Fresh, Unfixed Tissue: N/A
- Fluids: N/A
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.