• Immunohistochemistry (IHC)
p63 is a homologue of the p53 gene and is necessary for normal breast and prostate development. Unlike other markers of myoepithelial cells and basal cells, p63 immunoreactivity is localized to the nucleus of the cells, which can offer distinct advantages over cytoplasmic labeling in certain types of cases. p63, as a marker of myoepithelial and basal cells, is extremely useful in diagnostic surgical pathology, particularly when examining difficult breast biopsies and prostate biopsies. p63 is also a marker of squamous cell and erothelial carcinomas.
Turnaround time
Tech Only: 1 to 2 Days

Level of Service

  • Technical Only
New York Approved: Yes

Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

CPT Code(s)*

88342 x 1 or 88341 x 1

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Last Updated: January 22, 2025

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.