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MYD88 Mutation Analysis

  • Molecular
This test uses bi-directional sequencing on MYD88 exon 5, including detection of the common L265P mutation.
Turnaround time
7 Days

Level of Service

  • Global
New York Approved: Yes

Specimen Requirements

Bone Marrow Aspirate: 2 mL in EDTA tube.
Peripheral Blood: 5 mL in EDTA tube.
H&E slide (required) plus paraffin block.
Cut Slides: H&E slide (required) plus 5-10 unstained slides cut at 5+ microns.
Fresh Lymph Node or Needle Core Tissue Biopsy: 0.5-1 cm3 in RPMI.
Note on FFPE: Paraffin block is preferred. Do not use zinc fixatives. If submitting slides, please use positively-charged slides and 10% NBF fixative. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. Please select extract & hold - DNA if specimen hold service is desired. NYS clients please provide date and time of Collection.

CPT Code(s)*

81305

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Last Updated: August 05, 2025

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.

MYD88 Mutation Analysis