Alternative Name
c-MYC Amplification
Methodology
FISH
Test Description
Probes: MYC (8q24) | Centromere 8
Disease(s): Angiosarcoma
Clinical Significance
MYC gene dysregulation is frequently observed across various cancer types. In angiosarcoma, assessing MYC [c-MYC] amplification status provides diagnostic and prognostic information to distinguish post-radiation angiosarcoma from other angiosarcomas and non-neoplastic vascular proliferations.
Specimen Requirements
- Paraffin Block: Send paraffin block. Also send circled H&E slide for tech-only (required).
- Cut Slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Circle H&E slide for tech-only.
- Bone Marrow Aspirate: N/A
- Peripheral Blood: N/A
- Fresh, Unfixed Tissue: N/A
- Fluids: N/A
Storage & Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
CPT Code(s)*
88374x1 automated or 88377x1 manual.
Turnaround Time
3-5 Days
Level of Service
Global
Technical
New York Approved
No