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MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL
- Molecular
This test utilizes sequential testing including qualitative detection of JAK2 V617F, JAK2 Exon 12-14, CALR exon 9, and MPL exon 10.
Testing proceeds by reflex, with the next step triggered by a negative result or a weakly positive result of uncertain clinical significance; no further testing is performed once an informative result is obtained.
Testing is performed on plasma for increased sensitivity whenever possible.
Test Customization: Tests may also be ordered individually.
Specimen Requirements
Bone Marrow Aspirate: 2 mL in EDTA tube.
Peripheral Blood: 5 mL in EDTA tube.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Ship same day as drawn whenever possible. NYS clients please provide date and time of Collection.
CPT Code(s)*
81270, 81279, 81219, 81339 (as of 01/01/2021); Prior CPT Codes were 81270, 81403, 81219, 81402
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: August 05, 2025