Get in touch
Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.
JAK2 Exon 12-13 Mutation Analysis
- Molecular
RT-PCR and bi-directional sequencing to detect mutations in exons 12-13, corresponding to the majority of the JAK2 pseudokinase domain. Exon deletion mutations are detectable. Testing is performed on plasma for increased sensitivity whenever possible. V617F analysis is recommended before or concurrently with this test. Exon 12-13 Mutation Analysis may be ordered separately, with concurrent V617F testing, by reflex after negative V617F testing, or as part of the MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL. Testing is approved for specimens from the state of New York.
Turnaround time
7 Days
Level of Service
- Global
New York Approved: Yes
Specimen Requirements
Peripheral Blood: 5mL EDTA tube Bone Marrow: 2mL EDTA tube Note: Test is RNA-based. Please select Extract & Hold - RNA if specimen hold service is desired. If considering the MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL test as an add-on, we recommend adding Extract & Hold €“ DNA with Extract & Hold - RNA order.
Storage and Transportation
NYS clients please provide date and time of Collection. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Please select Extract & Hold - RNA if specimen hold service is desired.
CPT Code(s)*
81279 (as of 01/01/2021); Prior to CPT Code was 81403
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025