IDH1 mutations are frequent genetic alterations in low-grade diffuse gliomas and secondary glioblastoma (70%). This alteration is observed in fewer...
IHC
Bi-directional sequencing of the exon 4 mutation hotspot regions in both the IDH1 and IDH2 genes. IDH1 and IDH2 are analyzed concurrently. In hemat...
Molecular
IgA antibody reacts with immunoglobulin Ig alpha chains. It is useful in identifying leukemias, plasmacytomas and B-cell lineage lymphomas.
IgD antibody reacts with immunoglobulin Ig delta chains. This antibody is useful when identifying leukemias, plasmacytomas and B-cell lineage lymphoma...
IgG antibody reacts with immunoglobulin Ig gamma chains. This antibody may be useful in identifying plasma cytomas and B-cell lineage lymphomas, and ...
Autoimmune pancreatitis typically produces an enlarged pancreas with narrowing of the pancreatic duct, and can mimic carcinoma. It was shown that the ...
Probes: IgH (14q32) Disease(s): Lymphoma, NHL, multiple myeloma, MGUS
FISH
The IgH Clonality/MRD by NGS assay detects clonal populations of B-lymphocytes in a given patient sample through the analysis of the VDJ segment of...
Probes: IgH/BCL2 t(14;18)Disease(s): Follicular lymphoma, NHL
Probes: IgH/MAF t(14;16) Disease(s): Multiple myeloma, MGUS
Probes: IgH/MAFB t(14;20) This probe combination may be ordered separately or added to any of our mye Disease(s): Myel...
IgM antibody reacts with immunoglobulin Ig mu chains. This antibody is useful when identifying leukemias, plasmacytomas and B-cell lineage...
RT-PCR and bi-directional sequencing of the variable region of the immunoglobulin heavy chain for detection of mutation from germline sequence. The...
The Inherited Bone Marrow Failure Panel consists of next-gen sequencing of all coding regions of the following 58 genes, shown grouped by categories of gene function or primary associated disease. Note: Patient and physician or genetic counselor signatures on the NeoGenomics Consent for Hereditary Cancer Genetic Testing...
Anti-Inhibin alpha is an antibody against a peptide hormone which has a demonstrated utility in differentiating between adrenocortical tumors and rena...
Lack of nuclear expression of INI1 is characteristic of malignant rhabdoid tumors and epithelioid sarcomas.
INSM1 is a transcription factor that is a sensitive and specific marker for neuroendocrine tumors. It is a nuclear stain, and is as good if n...
Insulin is composed of a and b chains connected through the C-peptide. The main storage site for insulin is the pancreatic islets. Antibodies to insul...
Real-time RT-PCR for quantitative detection of the inv(16) CBFB-MYH11 fusion transcript. Positive results are reported as ratio of the amount of fu...