Alternative Name
HER2 neu
Methodology
FISH
Test Description

Probes: HER2 (17q11.2-q12) | 17 (Cen 17
Disease(s): Breast cancer

Clinical Significance

Determines anti-HER2 therapy.

Specimen Requirements
  • Pathology Report: A copy of the pathology report is required for HER2 testing (global cases only).
  • Bone Marrow Aspirate: N/A
  • Peripheral Blood: N/A
  • Fresh, Unfixed Tissue: N/A
  • Fluids: N/A
  • Paraffin block: Send paraffin block. Also send circled H&E slide for tech-only (required).
  • Cut slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Circle H&E slide for tech-only.
Storage and Transportation

Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

CPT Code(s)*
88374x1 automated. Codes may differ if manual analysis is performed.
Turnaround Time

3-5 days

Level of Service
Global
Technical

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.