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This antibody reacts with H. pylori on the surface and in the cytoplasm of epithelial cells of stomach biopsies. Studies have shown that H. pylori plays an important role in the etiology of chronic active gastritis and the development of peptic…
Immunohistochemistry (IHC)
H3K27me3 (trimethylation at lysine 27 of histone H3) is involved in the modification of DNA by protein Histone H3. Complete loss of H3K27me3 expression by immunohistochemistry can be useful in the diagnosis of malignant peripheral nerve sheath…
Immunohistochemistry (IHC)
Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGenomics and is not available for stand-alone testing. Markers are CD11c, CD19, CD20, CD22, CD25, CD45,…
Flow Cytometry
Available as global and tech-only. Please provide clinical history including the time after treatment. Prior immunophenotyping at NeoGenomics with Standard or Extended Flow Panel is strongly recommended. Clients who decline full phenotyping and…
Flow Cytometry
HBME1 is an anti-mesothelial monoclonal antibody that recognizes an unknown antigen on the microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesotheliomas in a thick membrane pattern. This antibody also…
Immunohistochemistry (IHC)
HCG-beta is secreted in large quantities by the placenta and normally is found in maternal circulation during early fetal development. Polyclonal Rabbit Anti-Human Chorionic Gonadotropin is intended for use in immunocytochemistry. The antibody…
Immunohistochemistry (IHC)
Hemoglobin A antibody reacts with the alpha chain of adult hemoglobin A. This antibody is useful in the detection of red blood cell precursors. Immunohistochemical localization of hemoglobin is excellent as an erythroid marker for the detection of…
Immunohistochemistry (IHC)
Hepatitis B virus belongs to the hepatovirus family and causes type B hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42 nm. Core antigens are localized within the nuclei, whereas the surface antigens are present in the…
Immunohistochemistry (IHC)
Hepatitis B virus, belongs to the hepatovirus family, and causes type B hepatitis. It is spherical in shape with a diameter of 42 nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigens in the…
Immunohistochemistry (IHC)
Anti-Hepatocyte Specific Antigen (HepPar1) recognizes both benign and malignant liver derived tumors such as hepatoblastoma, hepatocellular carcinoma and hepatic adenoma. It recognizes both adult and fetal liver tissue. The typical pattern is a…
Immunohistochemistry (IHC)
HER2, a member of the epidermal growth factor receptor family, is a transmembrane protein with tyrosine kinase activity. Gene amplification and protein overexpression of HER2 have been found in a variety of tumors. This test uses the Ventana PATHWAY…
Immunohistochemistry (IHC)
Probes: HER2 (17q11.2-q12) | Centromere 17 (Cen 17) Disease(s): Endometrial cancer, salivary duct carcinoma, ovarian cancer, serous carcinomas, and other various tumor types
FISH
This test uses the Ventana PATHWAY anti-HER-2/neu antibody (clone 4B5) for the semi-quantitative detection of HER-2 antigen in sections of FFPE normal and neoplastic tissue. The test is FDA-approved with the indication as an aid in the assessment of…
Immunohistochemistry (IHC)
Probes: HER2 (17q11.2-q12) | 17 (Cen 17) Disease(s): Breast cancer
FISH
HER2, a member of the epidermal growth factor receptor family, is a transmembrane protein with tyrosine kinase activity. Gene amplification and protein overexpression of HER2 have been found in a variety of tumors. This test uses the Ventana PATHWAY…
Immunohistochemistry (IHC)
Probes: HER2 (17q11.2-q12) | Centromere 17 (Cen 17) Disease(s): Colorectal cancer
FISH
Probes: HER2 (17q11.2-q12) | Centromere 17 (Cen 17) Disease(s): Gastric cancer, Gastroesophageal Adenocarcinoma, Gastroesophageal junction (GEJ) cancer
FISH
HER2, a member of the epidermal growth factor receptor family, is a transmembrane protein with tyrosine kinase activity. Gene amplification and protein overexpression of HER2 have been found in a variety of tumors, including gastric/gastroesophageal…
Immunohistochemistry (IHC)
HGAL is specifically expressed in the cytoplasm of germinal center B-cells, but is absent in mantle and marginal zone. This antibody is highly specific for germinal center B-cells and it is an ideal marker for the detection of germinal center-…
Immunohistochemistry (IHC)
Human Herpes Virus (HHV) 8 is the likely etiological agent of Kaposi’s sarcoma (KS), and is present in all cases. HHV 8 encodes a latent nuclear antigen (LANA) that is the product of the viral gene of 73. HHV8 has also been identified in…
Immunohistochemistry (IHC)
Markers are CD14, CD15, CD24, CD45, CD59, CD64, CD235a (Glycophorin A), and FLAER. In validation studies, this assay was shown to detect RBC and granulocyte PNH clones with frequency down to 0.01%.
Flow Cytometry
Probes: MYC (8q24). If rearranged, reflex to concurrent BCL2 (18q21) and BCL6 (3q27). Disease(s): B-cell lymphoma, double-hit lymphoma, triple-hit lymphoma Note: This test is available on a global basis. Tech-only clients may order probes…
FISH
Probes: BCL6 (3q27) | MYC (8q24) | BCL2 (18q21) | Optional probe: MYC/IgH/CEN8 t(8;14) Disease(s): B-cell lymphoma, double-hit lymphoma, triple-hit lymphoma
FISH
Antibody clone HMB45 recognizes a melanoma-specific antigen by reacting with melanoma cells, nevus cells and neonatal melanocytes. HMB45 is expressed on the majority of malignant melanoma cases as well as on tumors of melanocytic differentiation.
Immunohistochemistry (IHC)
Human Placental Lactogen (HPL) is a polypeptide hormone synthesized in syncytiotrophoblastic cells of placenta and has been used as a tissue marker for certain trophoblastic tumors.
Immunohistochemistry (IHC)