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Galectins are a structurally-related family of proteins; 14 different galectins have been characterized. They are cytoplasmic proteins and can be translocated into the nucleus. Gal-3 has been found overexpressed in most malignant thyroid neoplasms.…

Gastrin, a polypeptide hormone, occurs naturally in three forms: gastrin-14, gastrin-17 and gastrin-34. This antibody labels gastrin or gastrin-analogue producing cells in gastrin-secreting tumors and G cell hyperplasia.

GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. Among several other roles, GATA3 is involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the…

This antibody is specific to a 15kDa monomer protein called Gross Cystic Disease Fluid Protein-15 (GCDFP-15). GCDFP15 is expressed in apocrine epithelia, lacrimal, ceruminous and Moll’s glands, as well as in numerous serous cells of the…

The GCET1 gene codes for a serpin expressed in germinal center (GC) B-cells. GCET1 is highly restricted to a subset of GC B-cells and GC-derived lymphomas. It is preferentially expressed in follicular lymphoma (FL) and diffuse large B-cell lymphoma…

Glial Fibrillary Acidic Protein (GFAP) is the major protein found in astrocytes and its expression is evidence of astroglial origin and differentiation. Gliomas are the most common cerebral neoplasm in adults and include astrocytomas,…

Growth Hormone (GH) is produced by the somatotroph cells in the pituitary. This marker is a useful in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Special stain.

Glucagon antibody is used for the identification of tumors and hyperplasias of pancreatic islets. This antibody labels A cells of the endocrine mammalian pancreas. It reacts with glucagon in a large number of mammalian species.

Glucose transporter 1 (GLUT1) facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT-1 is expressed in many human tissues including those of the colon, lung, stomach, esophagus and breast. Overexpression of GLUT1…

Glutamine synthetase (GS) is strongly expressed in a majority of hepatocellular carcinoma, including cases of early HCC and low grade HCC.

Glycophorin A (sialoglycoprotein alpha) is one of two transmembrane proteins exposed on the outer surface of normal human erythrocytes. This monoclonal antibody reacts with an epitope located on the extracellular domain of glycophorin A and does not…

A useful marker to differentiate between benign (negative) and malignant (positive) liver diseases (HCCs).

Special stain.

Granzyme B antibody labels activated human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. This marker can be a useful tool for the identification of anaplastic large cell lymphoma, large granular lymphocytic leukemias, hepatosplenic T-…

Special stain. GMS (Grocott Methenamine-Silver Nitrate) Fungus Stain is used to demonstrate fungal organisms in tissue sections.