Displaying 1 - 73 of 73 tests
1p/19q Deletions for GliomaProbes: 1p36/1q25 |19q13/19p13
Disease(s): Oligodendroglioma
Ratios of p:q signals are determined for each chromosome to account for sectioning artifact. Deletion status is reported for each chromosome.
FISH
ALK for Lymphoma

Probes: ALK (2p23)
Disease(s): Anaplastic large cell lymphoma, NHL

FISH
ALK for NSCLCProbes: ALK (2p23)
Disease(s): Non-small cell lung carcinoma (NSCLC)
FISH
ALL Adult FISH Panel

Probes: TCF3/PBX1 (E2A/PBX1) t(1;19) | Trisomy or Tetrasomy 4, 6, 10, 17 (Cen 4, Cen 6, Cen 10, Cen 17) | MYC (8q24) | BCR/ABL1/ASS1 t(9;22) | MLL (11q23) | IgH (14q32) |
Disease(s): Acute lymphoblastic (lymphocytic) leukemia (B-cell ALL), B lymphoblastic lymphoma (LBL), adult
Probes may be ordered separately except Centromeres 4 and 17 are paired, and Centromeres 6 and 10 are paired.
Note: STAT processing is available by request for BCR-ABL1. Note STAT along with MD contact name and phone number to receive STAT results.
Note: CDKN2A (p16) Deletion FISH is also available and may be ordered separately. See details here.

FISH
ALL Pediatric FISH Panel

Probes: TCF3/PBX1 (E2A/PBX1) t(1;19) | Trisomy or Tetrasomy 4, 6, 10, 17 (Cen 4, Cen 6, Cen 10, Cen 17) | MYC (8q24) | BCR/ABL1/ASS1 t(9;22) | MLL (11q23) | ETV6/RUNX1 (TEL/AML1) t(12;21) | IgH (14q32)
Disease(s): Acute lymphoblastic (lymphocytic) leukemia (B-cell ALL), B lymphoblastic lymphoma (LBL), pediatric
Probes may be ordered separately except Centromeres 4 and 17 are paired, and Centromeres 6 and 10 are paired.
Note: STAT processing is available by request for BCR-ABL1. Note STAT along with MD contact name and phone number to receive STAT results.
Note: CDKN2A (p16) Deletion FISH is also available and may be ordered separately. See details here.

FISH
AML Favorable-Risk PanelProbes: RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Disease(s): Acute myeloid leukemia
Probes may be ordered separately.
FISH
AML FISH Panel (New York)

Probes: 5q-, -5 (5p15.2, 5q33-34) | 7q-, -7 (7q31, Cen 7) | Trisomy 8 (Cen 8) | MLL (11q23) | RUNX1T1/RUNX1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Probes may be ordered separately.
Disease(s): AML
Note: STAT processing is available by request for PML-RARA. Note STAT along with MD contact name and phone number to receive STAT results.

FISH
AML Non-Favorable Risk FISH Panel

Probes: RPN1, MECOM (3q21, 3q26.2) | 5q-, -5 (5p15, 5q31, 5q33 | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | DEK/NUP214 (CAN) t(6;9) | MLL (11q23) | ETV6 (12p13) | 17p- (TP53 17p13.1, NF1 17q11.2) | Probes may be ordered separately.
Disease(s):Acute myeloid leukemia

FISH
AML Standard FISH Panel

Probes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter) | RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Acute myeloid leukemia Probes may be ordered separately except +8 and 20q- which are combined.
Note: STAT processing is available by request for PML-RARA. Note STAT along with MD contact name and phone number to receive STAT results.

FISH
API2/MALT1 t(11;18)Probes: API2/MALT1 t(11;18)
Disease(s): MALT lymphoma, NHL
FISH
BCL2Probes: BCL2 (18q21)
Disease(s): B-cell lymphoma, non-Hodgkin lympoma (NHL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL)
FISH
BCL6 (3q27)Probes: BCL6 (3q27)
Disease(s): Diffuse large B-cell lymphoma, NHL
FISH
BCR/ABL1 t(9;22)

Probes: ABL1 (9q34); ASS1 (9q34; BCR (22q11.2)
Disease(s): CML, ALL, MPN
Note: For suspected ALL, STAT processing is available by request. Note STAT along with MD contact name and phone number to receive STAT results.

FISH
Bladder Cancer

Probes: +3 (Cen 3) | +7 (Cen 7) | p16 (9p21) | +17 (Cen 17)
Disease(s): Bladder cancer

FISH
BRAF Rearrangement

Probes: BRAF (7q34)
Disease(s): Brain cancer, thyroid cancer, melanoma

FISH
CBFB inv(16)Probes: CBFB inv(16), t(16;16)
Disease(s): AML, AMML (AML-M4E)
FISH
CCND1(BCL1)/IgH t(11;14)Probes: CCND1/IgH t(11;14)
Disease(s): Mantle cell lymphoma, NHL
FISH
CDKN2A (p16) Deletion FISH for ALL

Probes: CDKN2A (p16) (9p21) | Centromere 9
Disease(s): Acute Lymphoblastic Leukemia (ALL)

FISH
CDKN2A (p16) Deletion for Mesothelioma

Probes: CDKN2A (p16) (9p21) | Centromere 9
Disease(s):  Mesothelioma

FISH
Centromere 1 FISH for POC PloidyProbes: CEN 1 (1p11.1-q11.1)
Disease(s): Molar pregnancy vs. partial mole
This test is currently available on a global basis only.
FISH
CLL FISH PanelProbes: 6q- [SEC63 (6q21), MYB (6q23)] | ATM (11q22.3) | p53 (17p13.1) | Trisomy 12 (Cen 12) | 13q-/-13 (13q14, 13q34) | CCND1/IgH t(11;14) | Probes may be ordered separately (except 12 and 13 are tested together, and ATM is tested with p53).
Disease(s): Chronic lymphocytic leukemia
Note: This test was previously called CLL FISH Panel (non-New York). It is now New York state-approved and available to all clients.
FISH
DDIT3 (CHOP)Probes: DDIT3 (CHOP) (12q13)
Disease(s): Myxoid-round cell liposarcoma (M/RCLS)
FISH
DUSP22-IRF4 Rearrangement

Probes: DUPS22-IRF4 gene region at 6p25.3
Disease(s): Anaplastic Large Cell Lymphoma (ALCL), large B-cell lymphoma
 

FISH
EGFR AmplificationProbes: EGFR (7p11.2) | Centromere 7
Disease(s): Brain, lung, colorectal, gastric, breast cancers
FISH
Eosinophilia FISH PanelProbes: PDGFRa, CHIC2, FIP1L1 (4q12) | PDGFRb (5q33) | FGFR1 (8p11) | CBFB inv(16), t(16;16) | Probes may be ordered separately.
Disease(s): Lymphoid and myeloid neoplasms with eosinophilia, including: Chronic eosinophilic leukemia, eosinophilia, MPN, AML-NOS, lymphoblastic lymphoma, CMML, AML with inversion 16
FISH
EWSR1

Probes: EWSR1 (22q12)
Disease(s): Ewing sarcoma, primitive neuroectodermal tumor (PNET)

FISH
FGFR3/IgH t(4;14)Probes: FGFR3/IgH t(4;14)
Disease(s): Multiple myeloma, MGUS
FISH
HER2 Breast Cancer

Probes: HER2 (17q11.2-q12) | 17 (Cen 17
Disease(s): Breast cancer

FISH
HER2 Breast Equivocal FISH Panel

Probes: TP53 (17p13.1) | SMS Critical Region (SMSCR) (17p11.2) | Centromere 17 | RARA (17q21.1
Disease(s): Breast cancer
Testing is performed only on a global basis at this time.

FISH
HER2 Gastric & Non-Breast

Probes: HER2 (17q11.2-q12) | 17 (Cen 17)
Disease(s): Gastric cancer, gastroesophageal junction (GEJ) cancer, esophageal adenocarcinoma, and others

FISH
High-Grade B-Cell Lymphoma Reflex FISH Panel (Non-New York)

Probes: MYC (8q24). If rearranged, reflex to concurrent BCL2 (18q21) and BCL6 (3q27).
Disease(s): B-cell lymphoma, double-hit lymphoma, triple-hit lymphoma

Note: This test is available on a global basis. Tech-only clients may order probes individually.

FISH
High-Grade/Large B-Cell Lymphoma Panel (NY and non-NY)

Probes: BCL6 (3q27) | MYC (8q24) | IgH/BCL2 t(14;18) | Optional probes: MYC/IgH/CEN8 t(8;14) [available to all clients] and BCL2 (18q21) [non-New York clients only]
Disease(s): B-cell lymphoma, double-hit lymphoma, triple-hit lymphoma

FISH
IgH (14q32)

Probes: IgH (14q32)
Disease(s): Lymphoma, NHL, multiple myeloma, MGUS

FISH
IgH/BCL2 t(14;18)Probes: IgH/BCL2 t(14;18)
Disease(s): Follicular lymphoma, NHL
FISH
IgH/MAF t(14;16)Probes: IgH/MAF t(14;16)
Disease(s): Multiple myeloma, MGUS
FISH
IgH/MAFB t(14;20)

Probes: IgH/MAFB t(14;20)
This probe combination may be ordered separately or added to any of our mye
Disease(s): Myeloma, MGUSloma FISH panels.

FISH
Low-Grade/Small B-Cell Lymphoma FISH Panel

Probes: BCL6 (3q27) | CCND1/IgH t(11;14) IgH/BCL2 t(14;18) | MALT1 (18q21)
Probes may be ordered separately.
Disease(s): NHL, B-Cell Lymphoma, MCL, follicular lymphoma, MZL, MALT lymphoma

FISH
MALT1 (18q21)

Probes: MALT1 (18q21)
Disease(s): Marginal zone B-cell lymphoma, NHL

FISH
MDM2Probes: MDM2 (12q15) | Centromere 12
Disease(s): Liposarcoma
FISH
MDS Extended FISH Panel

Probes: RPN1, MECOM (3q21, 3q26.2) | 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | ETV6 (12p13) | 17p- (TP53 17p13.1, NF1 17q11.2) | +19 (19p13.2, 19q13) | 20q- (20q12, 20qter)
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Myelodysplastic syndrome

FISH
MDS FISH Panel (New York)Probes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (7q31, Cen 7) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter)
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Myelodysplastic syndrome
FISH
MDS Standard FISH PanelProbes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter)
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Myelodysplastic syndrome
FISH
MET FISHProbes: MET (7q31) | Centromere 7
Disease(s): Multiple solid tumor cancers including lung (NSCLC), gastric, esophageal, endometrial
FISH
MLL (11q23)Probes: MLL (11q23)
Disease(s): ALL, AML
FISH
MPN FISH Panel

Probes: PDGFRa, CHIC2, FIP1L1 (4q12) | PDGFRb (5q33) | FGFR1 (8p11) | BCR/ABL1 t(9;22) including ASS1 (9q34) | Probes may be ordered separately.
Disease(s): Myeloproliferative neoplasms

FISH
Multiple Myeloma IgH Complex FISH Panel (New York)

Probes: FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | IgH/MAF t(14;16) | Probes for each translocation may be ordered separately.                      Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize t(4;14) testing unless directed otherwise by our client.

FISH
Multiple Myeloma-MGUS FISH Panel (New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | +3, hyperdiploidy (Cen 3) | +5, hyperdiploidy (5p15.2, 5q33-34) | +9, hyperdiploidy (Cen 9) | 13q- (13q14, 13q34) | IgH (14q32) | p53 (17p-)
Probes may be ordered separately except +3 and +9 which are combined.
Disease(s): Plasma cell myeloma, multiple myeloma, MGUS
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize p53 testing unless directed otherwise by our client.

FISH
MYC (8q24)Probes: MYC (8q24)
Disease(s): Lymphoma, NHL, B-ALL
FISH
MYC/IgH/Cen 8 t(8;14)Probes: Trisomy 8 (Cen 8) | MYC/IgH t(8;14)
Disease(s): Burkitt lymphoma, NHL
FISH
MYCN (n-MYC) Amplification

Probes: MYCN (2p24.3) | Centromere 2
Disease(s): Brain cancer, neuroblastoma, alveolar rhabdomyosarcoma, small-cell lung cancer, prostate cancer.

FISH
NeoSITE™ BE Barrett's Esophagus FISH Panel

Probes: MYC (8q24) | p16 (CDKN2A at 9p21) | HER2 (ERBB2 at 17q12) | ZNF217 (20q13)
This 4-probe FISH assay is performed on cytology brushings from Barrett esophagus to determine patterns of chromosomal gain and loss suggestive of esophageal adenocarcinoma/high-grade dysplasia vs. low grade dyplasia/non-dysplastic tissue. Sensitivity is 86% and specificity is 67% for differentiating the high-risk from the low-risk groups. Sensitivity and specificity are higher when only nodules rather than the entire esophagus are brushed. Cells from nodular surfaces will be tested first (if available) and reported as a final result if positive, or testing will reflex to the pan brushing sample if negative.
Testing is approved for specimens from the state of New York.
Disease(s): Barrett's esophagus, esophageal adenocarcinoma.

FISH
NeoSITE™ Cervical FISH PanelProbes: TERC (3q26) | D5S630 (5p15) |CEN 7 (7p11.1-q11.1) | MYC (8q24) | ZNF217 (20q13)
Disease(s): Cervical neoplasia, ASCUS, LSIL, HSIL, CIN, cervical cancer
FISH
NeoSITE™ Melanoma

Probes: RREB1 (6p25) | MYC (8q24) | CDKN2A p16 (9p21) | Centromere 9 | CCND1 (11q13)
Disease(s): Melanoma
Read more about the NeoSITE Melanoma panel.

FISH
Non-Hodgkin's Lymphoma (NHL) FISH Panel

Probes: ALK (2p23) | BCL6 (3q27) | MYC (8q24) | CCND1/IgH t(11;14) | IgH (14q32) | IgH/BCL2 t(14;18) | MALT1 (18q21)
Probes may be ordered separately.
Disease(s): NHL

FISH
NUP98

Disease(s): Acute Myeloid Leukemia
Probes: NUP98 (11p15.4)

FISH
PDGFRA Amplification

Probes: PDGFRA (4q12) | Centromere 4
Disease(s): Brain cancer

FISH
PDGFRA RearrangementProbes: PDGFRA | CHIC2 | FIP1L1 (4q12) Disease(s): Chronic eosinophilic leukemia, MPN FISH
Plasma Cell Myeloma FISH Panel (non-New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | +5, hyperdiploidy (5p15) | +9, hyperdiploidy (9q22) | +15, hyperdiploidy (15q22) | 13q- (13q14, 13q34) | IgH (14q32) | 17p- (TP53 17p13.1, NF1 17q11.2)
Probes may be ordered separately except +5, +9 and +15 which are combined.
Global cases with IgH rearrangement will automatically reflex to the Plasma Cell Myeloma IgH Complex FISH Panel unless client has opted out.
Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize p53 testing unless directed otherwise by our client.
 

FISH
Plasma Cell Myeloma IgH Complex FISH Panel (non-New York)

Probes: FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | IgH/MAF t(14;16) | IgH/MAFB t(14;20)
Probes for each translocation may be ordered separately. 
This panel is available separately or by reflex after the Plasma Cell Myeloma FISH Panel if it detects IgH rearrangement.
Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize t(4;14) testing unless directed otherwise by our client.

FISH
Plasma Cell Myeloma Prognostic FISH Panel (New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | 13q- (13q14, 13q34) | IgH/MAF t(14;16) | 17p- (TP53 17p13.1, Cen 17) | Probes for each rearrangement may also be ordered separately.
Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize t(4;14) and TP53 testing unless directed otherwise by our client.

FISH
Plasma Cell Myeloma Prognostic FISH Panel (non-New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | 13q- (13q14, 13q34) | IgH/MAF t(14;16) | IgH/MAFB t(14;20) |17p- (TP53 17p13.1, NF1 17q11.2) | 
Probes may be ordered separately. 
Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize t(4;14) and TP53 testing unless directed otherwise by our client.
 

FISH
Plasma Cell Myeloma Risk Stratification FISH Panel (non-New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | IgH/MAF t(14;16) | IgH/MAFB t(14;20) | 17p- (TP53 17p13.1, NF1 17q11.2) | Probes may be ordered separately.
Disease(s): Plasma cell myeloma, multiple myeloma
Note: Plasma cell enrichment will be performed on bone marrow or blood samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection. If enriched samples are insufficient to complete the whole panel, NeoGenomics will prioritize t(4;14) and 17p-testing unless directed otherwise by our client.
 

FISH
PML/RARA t(15;17)

Probes: PML/RARA t(15;17)
Disease(s): AML, APL (AML-M3)
Note: PML-RARA FISH is performed STAT when ordered as a stand-alone test (outside a panel). Note MD contact name and phone number to receive STAT results.

FISH
PTEN

Probes: PTEN (10q23) | GRID1 (10q23.2) | Centromere 10
Disease(s): Prostate cancer, melanoma, squamous cell carcinoma of the head and neck (PTEN deletions)
This test may be ordered separately or as part of the NeoTYPE Solid Tumor Profiles (Breast, Colorectal, Gastric, Lung, Other)

FISH
RARA Break-ApartDisease(s): APL, AML
Probes: RARA (17q21)
FISH
RET FISHProbes: RET (10q11.2)
Disease(s): Lung cancer, thyroid cancer
FISH
ROS1Probes: ROS1 (6q22.1)
Disease(s): Non-small cell lung carcinoma (NSCLC)
FISH
RUNX1T1/RUNX1 (ETO/AML1) t(8;21)Probes: RUNX1T1/RUNX1 (ETO/AML1) t(8;21)
Disease(s): AML-M2
FISH
SS18 (SYT)Probes: SS18 (SYT) (18q11.2)
Disease(s): Synovial sarcoma
FISH
TCL1Probes: TCL1 (14q32.1)
Disease(s): mature T-cell leukemia, T-cell prolymphocytic leukemia (T-PLL), adult T-cell leukemia/lymphoma (ATLL)
FISH
TOP2AProbes: TOP2A (17q21-q22) | Cen 17 (17p11.1-q11.1)
Disease(s): Breast cancer
Note: Available as a global test only.
FISH
X/Y FISH for EngraftmentProbes: Centromere X | DYZ1
Disease(s): Sex-mismatched stem cell transplant
FISH
X/Y FISH for Molar Pregnancy

Probes: Centromere X | Centromere Y
Note: Testing is performed only on a global basis at this time.
Disease(s): Molar pregnancy (hydatidiform mole), partial mole, triploidy

FISH