Cytokeratin 19 (CK19) is a member of the type I acidic subfamily of keratins. It is expressed in various different human tissues. CK19 labels ductal and glandular epithelia, prostatic epithelia, and non-keratinizing squamous epithelia. This antibody is useful in the diagnosis of breast and cervical carcinoma. CK19 is not expressed in hepatocytes, therefore, antibody to CK19 is also useful in the distinction of liver metastasis from hepatocellular carcinomas.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.