CD14 stains normal macrophages/monocytes, granulocytes (weak), Langerhans cells, dendritic cells, and B cells. Positive staining in diseased cells comprises B-cell chronic lymphocytic leukemia (B-CLL), follicular center cell lymphoma, diffuse large B cell lymphoma (DLBCL), and acute myeloid leukemia (AML)-M4/M5.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.