Caldesmon is a regulatory protein found in smooth muscle and tissues which interacts with actin, myosin, tryopomyosin and calmodulin. Caldesmon antibody detects smooth muscle and tumors of smooth muscle, myofibroblastic and myoepithelial differentiation. This antibody is also useful in the differentiation of epithelioid mesothelioma from serous papillary carcinoma of the ovary.
- A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type
- One (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.