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BTK Inhibitor Acquired Resistance Panel
- Molecular
Concurrent bi-directional sequencing of hotpost regions in the BTK and PLC-gamma-2 genes. Analysis includes the BTK mutation C481S and surrounding regions corresponding to amino acids C464 to M509 and the following PLC-gamma-2 mutations and surrounding regions: R665W (W646 to S679), S707 (A681 to M743), and L845F (I839 to V860).
Turnaround time
10 Days
Level of Service
- Global
New York Approved: No
Specimen Requirements
Peripheral blood: 5 mL in EDTA tube. Bone marrow: 2 mL in EDTA tube. FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives. Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.
Storage and Transportation
Please select extract & hold - DNA if specimen hold service is desired. Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
CPT Code(s)*
81233, 81320
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025