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Alternative Name
B-Cell Acute Lymphoblastic Leukemia Flow Follow-Up Panel
Methodology
Flow Cytometry
Test Description

Available only as tech-only. Prior immunophenotyping at NeoGenomics with Standard or Extended Flow Panel is strongly recommended. Tech-only clients who push cases to global will be asked to provide previous flow cytometry report, previous pathology report, and/or clinical history notes. Markers are cCD3, CD5, CD10, CD11c, CD19, CD20, cCD22, CD23, CD34, CD45, cCD79a, kappa, lambda, cMPO, and nTdT (15 markers).

Clinical Significance

For B-cell acute lymphocytic leukemia (B-ALL) monitoring after diagnosis is established. This is not a minimal residual disease panel since the standard number of events is collected.

Specimen Requirements
  • Bone Marrow Aspirate: 1-2 mL EDTA. Sodium heparin is acceptable. Lithium heparin or ACD (pale yellow/no gel separator) is not acceptable. Please provide recent CBC report.
  • Peripheral Blood: 1-2 mL EDTA. Sodium heparin is acceptable. Lithium heparin or ACD (pale yellow/no gel separator) is not acceptable. Please provide recent CBC report.
  • Fresh Bone Marrow Core Biopsy: 1-2cm core (length) tissue in RPMI
  • Fresh/Unfixed Tissue: 0.2 cm3 minimum in RPMI
  • Fluids and FNAs: Equal parts RPMI and specimen volume
  • NY Clients: Please provide Date and Time of Collection.
  • Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Storage and Transportation

Specimens should be received at NeoGenomics within 72 hours from collection to assure sample integrity and acceptable cell viability. Note: New York State samples must be received within 48 hours from collection per NYS requirements. Ship same day as drawn whenever possible. Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

CPT Code(s)*
88184(x1), 88185(x14).
Turnaround Time

1 day

New York Approved
Yes
Level of Service
Technical

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.