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The InVisionFirst®-Lung liquid biopsy test is a 37-gene next-generation sequencing assay performed on cell-free circulating tumor DNA in peripheral blood to detect oncogenic driver mutations and therapy targets in non-small cell lung cancer (NSCLC). This assay demonstrated 98% concordance with tissue in clinical validation. Testing is performed by Inivata. SNVs + indel hotspots: ALK, AKT1, BRAF, CCND1, CTNNB1, EGFR, ERBB2, ESR1, FGFR2, FGFR3, GATA3, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KRAS, KIT, MAP2K1, MET, MYC, NFE2L2, NRAS, NTRK1, NTRK3, PDGFRA, PIK3CA, PPP2R1A, ROS1, U2AF1 SNVs + indel exon coverage: PTEN (70%), CDKN2A, STK11, TP53 (88-100%) Fusions: ALK, NTRK1, RET, ROS1 CNV: EGFR, ERBB2, FGFR1, MET including exon 14 deletion
Level of Service
Peripheral Blood: 10mL in Streck Cell-Free DNA BCT® Tube. 2 Tubes. Do not refrigerate.
Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
0388U
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 16, 2025