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NeoTYPE® Follicular Lymphoma Profile
- Next Generation Sequencing (NGS)
The NeoTYPE® Follicular Lymphoma Profile analyzes 16 genes through a combination of next-generation sequencing (NGS) and FISH as noted below. Test reports include a summary interpretation of all results together. FISH components may be ordered as "Tech-Only" by pathology clients who wish to perform the professional component. NGS (16 Genes): ARID1A, BCL2, BCL6, CDKN2A, CREBBP, EP300, EZH2, FAS, KMT2D, MAP2K1, MEF2B, PIK3CA, SOCS1, STAT6, TNFAIP3, and TNFRSF14For EZH2, the test can detect relevant mutations in Exons 16 and 18, including Y646N, Y646H, Y646F, Y646S, Y646C, A682G, and A692V. FISH probes: IgH/BCL2 t(14;18) | DUSP22-IRF4 (6p25.3) | TNFRSF14 (1p36).
Turnaround time
14 Days
Level of Service
- Global
New York Approved: No
Specimen Requirements
FFPE tissue: Paraffin block. 10% NBF fixative is the recommended fixative. Do not use zinc or mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies. Note: Test in TNA-based. Please select Extract & Hold - TNA if specimen hold service is desired.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Please select Extract & Hold - TNA if specimen hold service is desired.
CPT Code(s)*
81450x1; 88374x3 or 88377x3
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025