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MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL
- Molecular
Sequential testing panel including qualitative detection of JAK2 V617F, JAK2 Exon 12-14, CALR exon 9, and MPL exon 10. Testing proceeds by reflex, with the next step triggered by a negative result or a weakly positive result of uncertain clinical significance; no further testing is performed once an informative result is obtained. Testing is performed on plasma for increased sensitivity whenever possible. Tests may also be ordered individually (see separate listing). Testing is approved for specimens from the state of New York.
Turnaround time
7 to 10 Days
Level of Service
- Global
New York Approved: Yes
Specimen Requirements
Peripheral blood: 5 mL in EDTA tube. Bone marrow: 2 mL in EDTA tube. Note: Test is RNA-based, NOT suitable for Freeze & Hold option.
Storage and Transportation
Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
81270, 81279, 81219, 81339 (as of 01/01/2021); Prior CPT Codes were 81270, 81403, 81219, 81402
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025