Get in touch
Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.
Breast Cancer Index® (BCI)
- Molecular
Breast Cancer Index (BCI) is an RT-PCR assay performed on FFPE breast tumor tissue that integrates two gene expression-based biomarkers: 1) the HOXB13:IL17BR ratio (H/I), which is associated with tumor responsiveness to endocrine therapy; and 2) Molecular Grade Index (MGI), which consists of the average expression of five cell cycle-associated genes (BUB1B, CENPA, NEK2, RACGAP1 and RRM2) and provides quantitative and objective molecular assessment of tumor proliferative status.
Turnaround time
7 to 10 Days
Level of Service
- Global
New York Approved: Yes
Specimen Requirements
Paraffin Block: 1 Block sent with a cold pack. No zinc or mercury fixatives. H&E: 1 unstained slide cut at 4-5 microns required. Cut Slides: 4 to 5 unstained slides cut at 4-5 microns. 50-100 viable tumor cells per probe set. Positively charged slides in 10% NBF. No zinc or mercury fixatives.
Storage and Transportation
Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
Please contact Biotheranostics, Inc. at 877-886-6739.
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 15, 2025