• Immunohistochemistry (IHC)
Octamer Binding Transcription Factor 4 (OCT4, also known as OCT3/4, POU51) is a transcription factor and is expressed by early embryonic cells, germ cells, and stem cells. OCT4 is a nuclear marker of classical seminoma and embryonal carcinoma. It has excellent sensitivity and specificity for these two tumors, and can be used as the screen for these neoplasms when dealing with a metastatic tumor of unknown origin.
Turnaround time
1 Day

Level of Service

  • Technical Only
New York Approved: Yes

Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

CPT Code(s)*

88342 x 1 or 88341 x 1

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Last Updated: January 22, 2025

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.