• In Situ Hybridization (ISH)
This probe set labels all latent EBV-infected cells, including EBV-positive lymphoblastoid cell lines and EBV infected B-cell immunoblasts in infectious mononucleosis. It also reacts with EBV-associated undifferentiated nasopharyngeal carcinomas and with Reed-Sternberg cells in almost all EBV-associated Hodgkin lymphoma cases. Global interpretation is available on head and neck specimens only; Tech-Only testing is available for all samples.
Turnaround time
Global (head and neck only): 3 Days, Tech-Only (stain only): 2 Day

Level of Service

  • Global
  • Technical Only
New York Approved: Yes

Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and three (3) positively charged unstained slides, all cut at 4-5 microns. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

CPT Code(s)*

88365 x 1 or 88364 x 1

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Last Updated: January 22, 2025

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.