Advanced analytics enables unambiguous quantitative immune cell classification across different tissue types, accounting for different biomarker staining patterns in different population of cells. Additionally, algorithms are able to differentiate between cell populations in the tumor, stroma, and tumor margin. This enables computation of the distance of every cell from any regions in the tissue to distances between multiple populations of cell. Advanced data image analysis enables the answering of complex questions that would simply not be feasible to answer through traditional qualitative analysis.

NeoGenomics’ Pharma Services offers three platforms for analysis of multiplex IF images: Indica Halo & Visiopharm for analysis of Vectra® Polaris™ multiplex images, and NEO Image Analysis, which is optimized specifically for MultiOmyx™.

INDICA HALO®

  • User-friendly UI & Custom Development Workflow
  • Library of pre-configured modules available
  • HaloLink allows slide review and direct annotation by pathologists
  • Better fit for clinical trials because of the nature of the quality/regulatory requirements
  • Marketing partnership with NeoGenomics
  • Generates results very quickly for common tasks/simple analytics/single-plex

VISIOPHARM

  • Library of prebuilt apps available
  • Powerful tool set, optimal for more complex and custom analytics requirements
  • Can define non-cell objects in the tissue
  • AI packages that can be used for cell classification to increase accuracy
  • Clinical trial testing is feasible but requires more time and effort
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NEO IMAGE ANALYSIS

  • AI-based framework proprietary to NeoGenomics, Optimized for MultiOmyx
  • Highly customizable with complete control to accommodate new requirements
  • Adapted for IHC/CISH/dual IHC
  • NeoVUE compatible
  • RUO (software not validated to FDA standards)

Heatmaps

Nearest Neighbor Analysis

Platform

Indica Halo

Visiopharm

Neo IA

Currently Supporting Clinical Studies (retro)

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Clinical Studies (enrollment)

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N/A

Low order mIF, 2-6-plex (Polaris)

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High-plex mIF, ≥7 (MO)

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N/A

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Complexity of analytics tasks

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Direct annotation and slide review

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N/A

Defining non-cell objects

N/A

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