Comprehensive genomic profiling in advanced non-small cell lung cancer (aNSCLC)
Single biomarker testing rates in aNSCLC have increased slightly over the years. However, rates of comprehensive genomic profiling (CGP) continue to remain low despite recommendations from clinical guidelines.1
Broad molecular testing remains underutilized though many patients with aNSCLC are eligible for personalized therapy.
~50% of metastatic NSCLC patients are being tested for the five common biomarkers ALK, BRAF, EGFR, ROS1and PD-L11
Up to 55% of metastatic NSCLC patients have clinically relevant mutations2
The Lilly Lung Cancer Sponsored Testing Program provides access to CGP testing at no cost for eligible patients, exclusively through NeoGenomics
What is included in the Program?
One (1) tissue-based CGP test by NeoTYPE® DNA & RNA - Lung is provided per the eligibility criteria. This is an NGS-based profile targeting 50 genes most relevant to the management of NSCLC. PD-L1 by IHC is optional.
Follow-up with InVisionFirst®-Lung Liquid Biopsy is available should tissue-based testing prove insufficient for profiling.
No patient, health care program, or beneficiary shall be billed for these tests. Lilly will cover the cost of testing for eligible patients regardless of the test results and treatment decision.
Mobile Phlebotomy services are available for Liquid Biopsy at no cost to patients.
Who is eligible?
A patient with advanced or metastatic NSCLC is eligible if all of the following are true:
Patient has no known molecular biomarker
Patient has not had prior comprehensive biomarker testing
Patient has not been previously tested under this Program
Patient lives and receives treatment in the United States or a US Territory, except New York
Sorry, this Program is not yet available to New York patients.
What if my patient has already had biomarker testing?
If a patient had limited biomarker testing and results were negative, he or she is eligible. Patients who have had a positive biomarker result are not eligible for the Program. Patients who already had comprehensive genomic profiling are not eligible whether results were positive or negative.
Tissue results will be sent to the ordering physician’s office or laboratory within 14 days after the tissue sample is received. If liquid biopsy is performed, results can be expected 5-7 days after the blood is received.
How do I order testing?
In the NeoGenomics Online Orders system, choose NeoTYPE® DNA & RNA - Lung, Sponsored Testing Program and submit the pathology report and FFPE tissue specimen to NeoGenomics. If the tissue specimen is off-site, complete the Specimen Retrieval information (available in Online Orders 2.0).
To order with a printed requisition, please submit a completed copy of the Lung Cancer Sponsored Testing Program Request Form, pathology report, and FFPE tissue specimen to NeoGenomics. If the tissue specimen is off-site, complete the 3rd Party Specimen Location Specimen Retrieval section of the form and fax the form with the pathology report to 239.690.4237.
Who do I contact if I have a question?
NeoGenomics is here to help. For any technical questions or questions related to the Testing Program, please contact NeoGenomics Client Services at 866.776.5907.
To order NeoTYPE® DNA & RNA-Lung through the Lilly Sponsored Testing Program, please use this order form