Immunohistochemistry (IHC)
MyoD1 Methodology Immunohistochemistry (IHC) Test Description Nuclear expression of myogenic differentiation 1 (MyoD1) is restricted to skeletal muscle tissue and has been demonstrated to be a…
Immunohistochemistry (IHC)
Myogenin Methodology Immunohistochemistry (IHC) Test Description Expression of myogenin is restricted to cells of skeletal muscle origin. It is a useful marker for tumors of the muscle lineage, being…
Immunohistochemistry (IHC)
Napsin A Methodology Immunohistochemistry (IHC) Test Description Napsin A has a specific function in normal alveolar epithelium and is proposed to play a role in the proteolytic processing of…
FISH, Immunohistochemistry (IHC), Molecular
NeoTYPE® Cholangiocarcinoma Profile Alternative Name Cholangiocarcinoma Profile Methodology FISH Immunohistochemistry (IHC) Molecular Test Description…
Immunohistochemistry (IHC)
NeuN Methodology Immunohistochemistry (IHC) Test Description NeuN is a sensitive and specific marker of neuronal differentiation in brain tumors. Specimen Requirements…
Immunohistochemistry (IHC)
NF (Neurofilament) Methodology Immunohistochemistry (IHC) Test Description Neurofilaments (NFs) are the intermediate filaments of neurons and their processes. NFs are expressed in tumors of neural…
Immunohistochemistry (IHC)
NKX2.2 Methodology Immunohistochemistry (IHC) Test Description Homeobox protein NKX2.2 plays a critical role in neuroendocrine/glial differentiation. The NKX2.2 gene was recently identified as a…
Immunohistochemistry (IHC)
NKX3.1 Methodology Immunohistochemistry (IHC) Test Description NKX3.1 is a protein encoded by the NKX3.1 gene located on chromosome 8. NKX3.1 protein has been found to be positive in the vast majority…
Immunohistochemistry (IHC)
NSE (Neuron Specific Enolase) Methodology Immunohistochemistry (IHC) Test Description In normal tissue, most neurons and their axonal and dendritic processes stain strongly positive for Neuron…
Immunohistochemistry (IHC)
NUT Alternative Name Nuclear protein in testis Methodology Immunohistochemistry (IHC) Test Description Expression of nuclear protein in testis (NUT) is generally…
Immunohistochemistry (IHC)
OCT2 Methodology Immunohistochemistry (IHC) Test Description Octamer Binding Transcription Factor 2 (OCT2) is present in all B-cells expressing Ig. The combination of BOB1 and OCT2 stains is helpful…
Immunohistochemistry (IHC)
OCT4 Methodology Immunohistochemistry (IHC) Test Description Octamer Binding Transcription Factor 4 (OCT4, also known as OCT3/4, POU51) is a transcription factor and is expressed by early embryonic…
Immunohistochemistry (IHC)
Olig2 Methodology Immunohistochemistry (IHC) Test Description Olig2, a transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors,…
Immunohistochemistry (IHC)
p120 Catenin Methodology Immunohistochemistry (IHC) Test Description P120 Catenin is a tyrosine kinase which binds to E-cadherin within the cell membrane. It is detectable in the cell membranes of a…
Immunohistochemistry (IHC)
p16 Methodology Immunohistochemistry (IHC) Test Description p16 (p16 -INK4a, p16-MTS1, inhibitor of CDK4) is the product of the CDKN2 gene. It inhibits the progression of the cell cycle through the G1…
Immunohistochemistry (IHC)
p40 Methodology Immunohistochemistry (IHC) Test Description p40 antibody recognizes ΔNp63—a p63 isoform. It is equivalent to p63 in sensitivity for squamous cell carcinoma, but it is markedly superior…
Immunohistochemistry (IHC)
P501S Methodology Immunohistochemistry (IHC) Test Description P501S protein, also called the prostein, is a type IIIa plasma membrane protein which is exclusively expressed in cells of normal and…
Immunohistochemistry (IHC)
P504S Methodology Immunohistochemistry (IHC) Test Description Expression of P504S protein, or Alpha-methylacyl-CoA Racemase (AMACR), is found in prostatic adenocarcinoma but not in benign prostatic…
Immunohistochemistry (IHC)
p53 Methodology Immunohistochemistry (IHC) Test Description The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. Excess accumulation of the mutant p53 gene…
Immunohistochemistry (IHC)
p57 Methodology Immunohistochemistry (IHC) Test Description p57 (Kip 2, CDKN 1C) is an inhibitor of several G1 cyclin complexes and is a negative regulator of cell proliferation. The gene encoding…
Immunohistochemistry (IHC)
p63 Methodology Immunohistochemistry (IHC) Test Description p63 is a homologue of the p53 gene and is necessary for normal breast and prostate development. Unlike other markers of myoepithelial cells…
Immunohistochemistry (IHC)
pAKT (Phosphorylated AKT) Methodology Immunohistochemistry (IHC) Test Description AKT is a signal transduction protein that plays a central role in inhibiting apoptosis in a variety of tumor types.…
Immunohistochemistry (IHC)
Pan-Cytokeratin Alternative Name CK AE1/AE3 Methodology Immunohistochemistry (IHC) Test Description Monoclonal antibodies AE1 and AE3 recognize the acidic and basic…
Immunohistochemistry (IHC)
Pan-TRK Alternative Name TRKA, TRKB, TRKC Methodology Immunohistochemistry (IHC) Test Description Pan-TRK (clone EPR17341) is directed against the C-terminal region…
Immunohistochemistry (IHC)
Parafibromin Methodology Immunohistochemistry (IHC) Test Description Complete absence of nuclear staining for parafibromin is diagnostic of parathyroid carcinoma or an HPT-JT-related tumor (…