Test by Disease - Thyroid

54 Tests in Listing


Alcian Blue

Special stain. Alcian blue is intended to identify weakly sulfated mucins in tissue samples.

IHC

BerEP4

Ber-EP4 recognizes two glycoproteins of 34 and 49 kDa present on the surface and the cytoplasm of all epithelial cells except the superficial layers ...

IHC

BG8

This antibody is specific for the Lewis Y (Type 2 Chain) carbohydrate antigen. Lewis Y has been evaluated as a clinical marker for the diagnosis and p...

IHC

BRAF Mutation Analysis

Bi-directional sequencing of exon 15 of the BRAF gene, which includes qualitative detection of V600 mutations E, K, D, and others, plus other signific...

Molecular

BRAF Rearrangement

Probes: BRAF (7q34)
Disease(s): Brain cancer, thyroid cancer, melanoma

FISH

BRAF V600E

A monoclonal antibody (VE1) against mutant BRAF (V600E) permits fast assessment of the mutant protein expression throughout a tumor sample in hairy ce...

IHC

Calcitonin

Calcitonin is secreted by thyroidal parafollicular cells of neuroectodermal origin, probably in response to hypercalcemia. The IHC demonstration of ca...

IHC

CAM 5.2 (CK LMW)

Anti-Cytokeratin (CAM 5.2) has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, Mr 48 and 52 Kd. Cytoker...

IHC

CD1a

Individual antibodies are for add-on purposes only.

Flow

CD31

CD31 is a 130kDa transmembrane glycoprotein that is shared by vascular lining cells, megakaryocytes and platelets. This marker is highly restricted to...

IHC

CD5

Individual antibodies are for add-on purposes only.

Flow

Chromogranin A

Chromogranin is present in several elements of the diffuse neuroendocrine system (DNES), including anterior pituitary, thyroid perifollicular C cells,...

IHC

CK AE1/AE3

Monoclonal antibodies AE1 and AE3 recognize the acidic and basic subfamilies of cytokeratin, respectively, thus the combination of these two antibodie...

IHC

CK HMW (CK903/34BE12)

CK903 (34betaE12) is a high molecular weight cytokeratin present in all squamous epithelium and their carcinomas. This antibody recognizes cytokeratin...

IHC

CK19

Cytokeratin 19 (CK19) is a member of the type I acidic subfamily of keratins. It is expressed in various different human tissues. CK19 labels ductal ...

IHC

CK20

Cytokeratin 20 (CK20) positivity is seen in the majority of adenocarcinomas of the colon, mucinous ovarian carcinomas, transitional cell, and Merkel c...

IHC

CK5/6

D5/16 B4 clone of CK5/6 antibody reacts strongly with cytokeratins 5 and 6. Cytokeratin 5/6 have been found valuable for the distinction between low d...

IHC

CK7

Cytokeratin 7 (CK7) antibody reacts with proteins that are found in most ductal, glandular and transitional epithelium of the urinary tract and bile d...

IHC

EMA

Epithelial Membrane Antigen (EMA) antibody stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squ...

IHC

FOXP3

FOX P3 is expressed at a high level in CD25 positive/CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absen...

IHC

Galectin 3

Galectins are a structurally-related family of proteins; 14 different galectins have been characterized. They are cytoplasmic proteins and can be tra...

IHC

GNAS Mutation Analysis

Bi-directional sequencing of exons 8 and 9 of the GNAS gene to detect mutation hot spots in codons R201 and Q227.

Molecular

HBME1

HBME1 is an anti-mesothelial monoclonal antibody that recognizes an unknown antigen on the microvilli of mesothelioma cells. It stains normal mesothel...

IHC

HRAS Mutation Analysis

Bi-directional sequencing of HRAS exons 2 and 3 which includes sites of common activating mutations in codons 12, 13, 59 and 61.

Molecular

IDH1 & IDH2 Mutation Analysis

Bi-directional sequencing of the exon 4 mutation hotspot regions in both the IDH1 and IHD2 genes. IDH1 and IDH2 are analyzed concurrently. In hemat...

Molecular

Ki67

Ki67 is a nuclear protein that is expressed in proliferating cells. Ki67 is preferentially expressed during late G1, S, M, and G2 phases of the cell ...

IHC

MSA

Muscle Specific Actin (MSA) antibody recognizes the alpha and gamma isotypes of skeletal, cardiac, and smooth muscle cells. It is non-reactive with ot...

IHC

NeoARRAY™ SNP/Cytogenetic Profile

The NeoARRAY SNP/Cytogenetic Profile is available for hematological, solid tumor, and pregnancy loss indications. With the best genome-wide coverage a...

Molecular

NeoLAB™ Solid Tumor Monitor - Liquid Biopsy

The NeoLAB™ Solid Tumor Monitor is a blood test that uses cell-free circulating tumor DNA (ctDNA) or RNA in combination with next-generation ...

Molecular

NeoTYPE™ Cancer Exome Profile

The NeoTYPE™ Cancer Exome Profile is performed by massive parallel sequencing of the coding regions in 4813 different cancer related genes. Test order...

Molecular

NeoTYPE™ Discovery Profile for Solid Tumors

This test is performed by the sequencing of select exons of the genes listed unless another method is noted. ABL1, ABL2, ACVR1B, AKT1, AKT2, AKT3, ...

Molecular

NeoTYPE™ Other Solid Tumor Profile

This test is performed by the sequencing of select exons of the genes listed unless another method is noted. AKT1, BRAF, EGFR, FGFR1, FGFR2, FGFR3,...

Molecular

NeoTYPE™ Precision Profile for Solid Tumors

The NeoTYPE™ Precision Profile for Solid Tumors utilizes next-generation sequencing to detect mutations in the following 48 genes: ABL1, AKT1...

Molecular

NeoTYPE™ Thyroid Profile

This test is performed by the sequencing of select exons of the genes listed unless another method is noted. AKT1, ALK, BRAF, CTNNB1, ERBB2, ERBB4,...

Molecular

NGS ALK, NTRK, RET, ROS1 Fusion Profile

The NGS ALK, NTRK, RET, ROS1 Fusion Profile is a targeted next-generation sequencing panel that detects significant translocations in the genes ALK (f...

Molecular

NGS ALK, RET, ROS1 Fusion Profile

The NGS ALK, RET, ROS1 Fusion Profile is a targeted next-generation sequencing panel that detects significant translocations in the genes ALK (fusions...

Molecular

NGS Thyroid Fusion Profile

The NGS Thyroid Fusion Profile is a targeted next-generation sequencing panel that detects significant translocations in the genes NTRK1 (fusions of e...

Molecular

NRAS Exon 4 Mutation Analysis

Bi-directional sequencing of NRAS exon 4 is performed using PCR primers designed to target hotspot mutations in codons 117 and 146, among other reg...

Molecular

NRAS Mutation Analysis

Bi-directional sequencing of NRAS exons 2 and 3 which includes sites of common activating mutations in codons 12, 13, 59, and 61.

Molecular

NSE (Neuron Specific Enolase)

In normal tissue, most neurons and their axonal and dendritic processes stain strongly positive for Neuron Specific Enolase (NSE), with the exception ...

IHC

p21

p21 is a cyclin dependent protein kinase inhibitor and is a member of a family of proteins that functions to slow down cell division. p21 is found in ...

IHC

p53

The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. Excess accumulation of the mutant p53 gene product results ...

IHC

PAX8

The PAX8 gene is a member of the paired box (PAX) family of transcription factors. This family plays critical roles during fetal development an...

IHC

pHistone H3 (PHH3)

Phosphohistone H3 (PHH3) is a marker of cells in the late G2-M phase of the cell cycle. It is not expressed in apoptotic cells which may be confused w...

IHC

PIK3CA Mutation Analysis

Bi-directional sequencing of PIK3CA exons 1, 9, and 20 which are the most commonly-mutated regions of the gene.

Molecular

PTEN Mutation Analysis

Bi-directional sequencing of all exons (1-9) of the PTEN gene. For solid tumors, enrichment is performed befor...

Molecular

RET FISH

Probes: RET (10q11.2)
Disease(s): Lung cancer, thyroid cancer

FISH

Synaptophysin

Antibody to synaptophysin reacts with neuroendocrine neoplasms of neural as well as epithelial types. In combination with chromogranin A and NSE antib...

IHC

TERT Promoter Mutation Analysis

Bi-directional Sanger sequencing is performed using PCR primers designed to target mutations in the promoter region of TERT.

Molecular

Thyroglobulin (TGB)

This antibody labels thyroglobulin (TGB) in follicular epithelial cells of the thyroid and colloid. Thyroglobulin antibody is useful in positive ident...

IHC

TP53 Mutation Analysis

Bi-directional sequencing of TP53 exons 4-9.

Molecular

TTF1

Thyroid Transcription Factory (TTF1) is found only in thyroid and thyroid tumors regardless of histologic type, as well as in lung carcinomas, includ...

IHC

Universal Fusion/Expression Profile

The Universal Fusion/Expression Profile is a targeted RNA sequencing panel that utilizes next-generation sequencing (NGS) to detect all relevant fu...

Molecular

Vimentin

Vimentin is the major intermediate filament in a variety of mesenchymal cells, including endothelial cells, all fibroblastic cells, macrophages, Serto...

IHC

 

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