Alphabetically - p

60 Tests in Listing


p120 Catenin

P120 Catenin is a tyrosine kinase which binds to E-cadherin within the cell membrane. It is detectable in the cell membranes of a wide variety of cel...

IHC

p16

p16 (p16 -INK4a, p16-MTS1, inhibitor of CDK4) is the product of the CDKN2 gene. It inhibits the progression of the cell cycle through the G1 ph...

IHC

p21

p21 is a cyclin dependent protein kinase inhibitor and is a member of a family of proteins that functions to slow down cell division. p21 is found in ...

IHC

p27

p27 (KIP1) belongs to the family of cell cycle regulators that cause cell cycle arrest in G1 phase. p27 promotes apoptosis, plays a role in terminal d...

IHC

p40

p40 antibody recognizes δNp63—a p63 isoform. It is equivalent to p63 in sensitivity for squamous cell carcinoma, but it is markedly superior to ...

IHC

P501S

P501S protein, also called the prostein, is a type IIIa plasma membrane protein which is exclusively expressed in cells of normal and malignant pro...

IHC

P504S

Expression of P504S protein, or Alpha-methylacyl-CoA Racemase (AMACR), is found in prostatic adenocarcinoma but not in benign prostatic tissue. It has...

IHC

p53

The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. Excess accumulation of the mutant p53 gene product results ...

IHC

p57

p57 (Kip 2, CDKN 1C) is an inhibitor of several G1 cyclin complexes and is a negative regulator of cell proliferation. The gene encoding human p57 is ...

IHC

p63

p63 is a homologue of the p53 gene and is necessary for normal breast and prostate development. Unlike other markers of myoepithelial cells and basal ...

IHC

pAKT (Phosphorylated AKT)

AKT is a signal transduction protein that plays a central role in inhibiting apoptosis in a variety of tumor types. Constitutive activation of AKT (p...

IHC

Pan Melanoma (S100 + Melan A + Tyrosinase)

The Pan Melanoma staining combination increases sensitivity for melanomas. Since many skin biopsies are small, the triple stain conserves valuable tis...

IHC

Pan Melanoma/Ki67

Pan Melanoma/Ki67 serves as a tool to identify the proliferation rate of melanocytic lesions. A high Ki67 rate of a melanocytic lesion raises the poss...

IHC

Pancreatic Polypeptide (PP)

Pancreatic polypeptide (PP) is secreted by PP-cells of islet. It is also found in pancreatic acinar tissue and ductal epithelium. This antibody is use...

IHC

Parafibromin

Complete absence of nuclear staining for parafibromin is diagnostic of parathyroid carcinoma or an HPT-JT-related tumor (hyperparathyroidism-jaw tumor...

IHC

Parvovirus

This monoclonal antibody clone, R92F6, recognizes a capsid protein of human parvovirus B19. Therefore, this antibody will be useful in detection of pa...

IHC

PAX2

Paired Box 2 (PAX2) is a transcription factor that is essential for kidney development. In kidneys of normal adult, Pax2 protein expression is limited...

IHC

PAX5

Paired Box 5 (PAX5) is a B-cell specific activator protein (BSAP). In early stages of B-cell development, PAX5 influences the expression of several B-...

IHC

PAX8

The PAX8 gene is a member of the paired box (PAX) family of transcription factors. This family plays critical roles during fetal development an...

IHC

PD1

Programmed death-1 (PD-1) is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PD-1 is a marker of angioimmunoblastic lymphoma and sugg...

IHC

PDGFR Alpha (Platelet Derived Growth Factor Receptor Alpha)

Activated receptors control cell growth, migration and differentiation and may be a useful prognostic marker as well as a therapeutic target for d...

IHC

PDGFRA Amplification

Probes: PDGFRA (4q12) | Centromere 4
Disease(s): Brain cancer

FISH

PDGFRa Mutation Analysis

Bi-directional sequencing of exons 12 and 18 of the PDGFRA (platelet-derived growth factor alpha) gene. These ...

Molecular

PDGFRA Rearrangement

Probes: PDGFRA | CHIC2 | FIP1L1 (4q12) Disease(s): Chronic eosinophilic leukemia, MPN

FISH

PD-L1 28-8 FDA (OPDIVO®)

PD-L1 IHC 28-8 pharmDx is a qualitative immunohistochemical assay using Monoclonal Rabbit Anti-PD-L1, clone 28-8 intended for use in the detection of ...

IHC

PD-L1, 22C3 FDA (KEYTRUDA®)

PD-L1 IHC 22C3 pharmDx is a qualitative immunohistochemical assay using Monoclonal Mouse Anti-PD-L1, Clone 22C3 intended for use in the detection of P...

IHC

PD-L1, SP142 FDA (TECENTRIQ®)

The VENTANA PD-L1 (SP142) Assay is a qualitative immunohistochemical assay using rabbit monoclonal anti-PD-L1 clone SP142 intended for use in the a...

IHC

Perforin

Perforin is a protein found in cytoplasmic granules of cytotoxic T-lymphocytes (CTLs). CTLs bind to cells that express foreign antigens and induce the...

IHC

PGP9.5

Protein Gene Product 9.5 (PGP9.5) is also known as ubiquitin C-terminal hydrolase 1 (UCHL-1). Expression of PGP9.5 is highly specific to neurons and t...

IHC

PgR

Progesterone Receptor (PR) belongs to a superfamily of nuclear hormone receptors. Estrogen Receptor (ER) induces PR expression, therefore, PR status s...

IHC

pHistone H3 (PHH3)

Phosphohistone H3 (PHH3) is a marker of cells in the late G2-M phase of the cell cycle. It is not expressed in apoptotic cells which may be confused w...

IHC

PIK3CA Mutation Analysis

Bi-directional sequencing of PIK3CA exons 1, 9, and 20 which are the most commonly-mutated regions of the gene.

Molecular

PLAP

Normally human Placental Alkaline Phosphatase (PLAP) is produced by syncytiotrophoblasts after the twelfth week of pregnancy. PLAP is expressed by bot...

IHC

Plasma Cell Add-On Flow Panel

Available as global and tech-only. This add-on panel is available to clarify findings on samples currently having flow cytometry analysis at NeoGen...

Flow

Plasma Cell Follow-Up Flow Panel

Available as global and tech-only. Prior immunophenotyping at NeoGenomics with Standard or Extended Flow Panel is strongly recommended. Clients who...

Flow

Plasma Cell Myeloma Prognostic FISH Panel (New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | 13q- (13q14, 13q34) | IgH/MAF t(14;...

FISH

Plasma Cell Myeloma Prognostic FISH Panel (non-New York)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | 13q- (13q14, 13q34) | IgH/MAF t(...

FISH

Plasma Cell Myeloma Risk Stratification FISH Panel (non-NY)

Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | IgH/MAF t(14;16) | IgH/MAFB t(14;20) | 17p- (TP53 17p...

FISH

PLC-Gamma-2 Mutation Analysis

Bi-directional sequencing to detect mutations in exons 19, 20, and 24, covering amino acid ranges W646 to S679, A681 to M743, and I839 to V860. Testing is available separately or in combination with the BTK Inhibitor Acquired Resistance Panel....

Molecular

PML/RARA t(15;17)

Probes: PML/RARA t(15;17)
Disease(s): AML, APL (AML-M3)
Note: PML-RARA FISH is perfo...

FISH

PML-RARA Translocation, t(15;17)

Real-time RT-PCR for quantitative detection of the t(15;17) PML-RARA fusion transcript. Both long and short isoforms of the fusion transcript are d...

Molecular

PMS2

PMS2, also known as PMS1 protein homologue 2, is a DNA mismatch repair (MMR) protein. The PMS2 protein forms a heterodimer with the MLH1 protein which...

IHC

PMS2 Mutation & Del/Dup Analysis

This test is performed by sequencing the entire PMS2 gene using next-gen sequencing complemented by conventional Sanger sequencing or other molecular methodologies to detect point mutations, small insertions/deletions, and large deletions/duplications. Testing is also available in the Lynch Syndrome panel which includes EPCAM, MLH1, MSH2, MSH6, and PMS2. Note: Patient and physician or genetic counselor signatures on the NeoGenomics Consent for Hereditary Cancer Genetic Testing...

Molecular

Pneumocystis Carinii ( Jiroveci)

This antibody is specific to P. carinii (P. Jiroveci). It stains P. carinii distinctly. The staining pattern is visualized as homogeneou...

IHC

Prealbumin (TTR)

Prealbumin (Transthyretin, TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). The ...

IHC

Prolactin

Prolactin is a growth factor secreted by the anterior pituitary that is necessary for the proliferation and differentiation of the mammary glands. Pro...

IHC

Prostate Triple Stain

The combination of p63 + CK HMW + P504S (PIN-4 cocktail) can be extremely useful for diagnosing prostatic intraepithelial neoplasia (PIN) and/or prost...

IHC

PSA

Prostate specific antigen (PSA) is a glycoprotein with a molecular weight of 33-34kDa. It is restricted to the cytoplasm of acinar and ductal epithel...

IHC

PSAP/HPAP

Prostate specific acid phosphatase/human prostatic acid phosphatse (PSAP/HPAP) is a 100kDa glycoprotein present in high concentration in the prostate ...

IHC

PSMA

Prostate specific membrane antigen (PSMA) is a 750 amino acid type II membrane glycoprotein with folate hydrolase and neuropeptidase activity. PSMA is...

IHC

PTEN

Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene that is mutated in a wide range of cancers. PTEN plays a role in cell proliferation, ...

IHC

PTEN

Probes: PTEN (10q23) | GRID1 (10q23.2) | Centromere 10
Disease(s): Prostate cancer, melanoma, squamous cell carcinoma of the head and neck (PTEN deletions)
This test may be ordered separately or as part of the NeoTYPE Solid Tumor Profiles...

FISH

PTEN Mutation Analysis

Bi-directional sequencing of all exons (1-9) of the PTEN gene. For solid tumors, enrichment is performed befor...

Molecular

PTH

Parathyroid hormone (PTH) is expressed in normal parathyroid, parathyroid adenomas and primary and secondary hyperplasia of parathyroid. This antibod...

IHC

PTPN11 Mutation Analysis

Bi-directional sequencing of exons 2-4 of PTPN11.

Molecular

PU.1

PU.1 is a transcription factor that has been shown to be important for normal B-cell development. The absence of PU.1 results in a total block of B-ce...

IHC

 

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